Generic Method for Modular Surface Modification of Cellulosic Materials in Aqueous Medium by Sequential "Click" Reaction and Adsorption
Generic Method for Modular Surface Modification of Cellulosic Materials in Aqueous Medium by Sequential "Click" Reaction and Adsorption
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DOI：
10.1021/bm201661k
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发表时间：
2012-03-01
影响因子：
6.2
通讯作者：
Laine, Janne
中科院分区：
文献类型：
--
作者：
Filpponen, Ilari;Kontturi, Eero;Laine, Janne
提出了一种在水介质中对纤维素材料进行非均相表面改性的通用方法，该方法适用于广泛的功能化。在第一步中，用叠氮化物或炔官能度改性的羧甲基纤维素（CMC）吸附在纤维素基底上，从而为叠氮化物-炔环加成点击反应提供反应性位点。在第二步中，具有互补点击单元的功能单元在由点击改性的CMC包覆的纤维素表面上反应。选择不同的纤维素底物上的模型功能化示出证明的方法的一般性。通过依次组合稳健的物理吸附（“物理点击”）和稳健的化学反应（“化学点击”）的概念允许用几乎任何叠氮化物或炔改性的分子对纤维素基底进行通用、简单和环境友好的改性，甚至用几种类型的单元进行官能化。
A generic approach for heterogeneous surface modification of cellulosic materials in aqueous medium, applicable for a wide range of functionalizations, is presented. In the first step, carboxymethyl cellulose (CMC) modified with azide or alkyne functionality, was adsorbed on a cellulosic substrate, thus, providing reactive sites for azide-alkyne cycloaddition click reactions. In the second step, functional units with complementary click units were reacted on the cellulose surface, coated by the click-modified CMC. Selected model functionalizations on diverse cellulosic substrates are shown to demonstrate the generality of the approach. The concept by sequentially combining the robust physical adsorption ("physical click") and robust chemical reaction ("chemical click") allows versatile, simple, and environmentally friendly modification of a cellulosic substrate with virtually any azide- or alkyne-modified molecule and even functionalization with several types of units.