A high-throughput whole-body PET scanner using flat panel PS-PMTS
A high-throughput whole-body PET scanner using flat panel PS-PMTS
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DOI：
10.1109/tns.2004.829787
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发表时间：
2004-06-01
影响因子：
1.8
通讯作者：
Tanaka, E
中科院分区：
文献类型：
--
作者：
Watanabe, M;Shimizu, K;Tanaka, E
研制了一种用于全身研究的新型正电子发射断层扫描仪。该扫描仪有720个块探测器，每个块探测器由一个平板位置敏感光电倍增管和一个16×8 BGO晶体阵列组成。探测器系统由12层轴向堆叠的块探测器环组成，每个环由60个块探测器的圆形阵列组成。由于每个块探测器环包含8个晶环，因此探测器环的总数为96个，轴向视场(FOV)为685 mm，足以通过两步扫描测量全身。探测器环直径1020 mm，轴向FOV直径600 mm。在块检测器环之间放置粗片间隔，在保持较高检测灵敏度的同时有效地减少散布的符合事件；采用并行16台PC机进行数据采集和处理，以处理大量的事件数据。将采集到的三维数据用傅立叶反投影算法转换成二维数据集，然后用快速迭代算法“戏剧”进行重建。扫描后5min内获得全身重建图像，使用粗略间隔，NEMA NIJ2-2001标准测量的散射分数为31.4%，明显低于无间隔的三维正电子发射计算机断层扫描。系统灵敏度为9.72cps/kBq，在10.5kBq/ml时，直接随机相减法的噪声当量计数率峰值计数为113.6 kCps。
A new positron emission tomography (PET) scanner for whole-body studies has been developed. The scanner has 720 block detectors, each of which consists of a flat panel position-sensitive photomultiplier and a 16 x 8 BGO crystal array. The detector system is composed of 12 layers of block detector rings stacked axially, and each ring consists of a circular array of 60 block detectors. Since each block detector ring contains eight crystal rings, the total number of detector rings is 96 and the axial field of view (FOV) is 685 mm, which is sufficient to measure a whole-body with two steps of scan. The detector ring diameter is 1020 mm and the transaxial FOV is 600 mm in diameter. Coarse slice septa are placed between the block detector rings, which are effective to reduce scattered coincidence events while keeping a high detection sensitivity.Parallel 16 personal computers are used for the data acquisition and processing to deal with a large amount of event data. The acquired data in 3-D manner are converted to 2-D data set with Fourier rebinning algorithm and reconstructed with a fast iterative algorithm "DRAMA". The reconstructed images for the whole body are obtained within 5 min after the scan.By using the coarse septa, the scatter fraction measured with NEMA NIJ2-2001 standard was 31.4% whose value was significantly lower than that of 3-D PET without septa. The system sensitivity was 9.72 cps/kBq, and the peak counts of the noise equivalent count rate used with direct random-subtraction was 113.6 kcps at 10.5 kBq/ml.