Ganglioneuroma in the Urinary Bladder of a Dog
Ganglioneuroma in the Urinary Bladder of a Dog
复制标题
DOI：
10.1292/jvms.10-0523
复制
发表时间：
2011-06-01
影响因子：
1.2
通讯作者：
Yanai, Tokuma
中科院分区：
文献类型：
--
作者：
Sakai, Hiroki;Yonemaru, Kayoko;Yanai, Tokuma
一个11岁的男性拉布拉多猎犬慢性少尿。超音波检查发现膀胱颈部有一突出的肿块。进行膀胱切开术，并通过手术缝线结扎切除肿块。组织学检查发现肿瘤内有明显的病灶，神经节细胞数量不等，雪旺氏细胞与细纤维交织成束。神经节细胞呈神经元特异性烯醇化酶和神经丝阳性。雪旺氏细胞波形蛋白、S-100蛋白和胶质细胞酸性蛋白阳性。因此，根据神经元细胞分化的肿瘤分类，泌尿系肿瘤被诊断为神经节细胞瘤。
An 11-year-old male Labrador retriever presented with chronic oliguria. Ultrasonography findings revealed a protruding mass at the neck of the urinary bladder. A cystotomy was performed, and the mass was removed by ligation with surgical sutures. Histopathological examination revealed conspicuous foci with a variable number of ganglion cells in the tumor and abundant interwoven bundles of schwannian cells with fine fibers. The ganglion cells were positive for neuron-specific enolase and neurofilament. The schwannian cells were positive for vimentin, S-100 protein, and glial fibrillary acidic protein. Thus, according to the classification of tumor with neuronal cell differentiation, the urinary tumor was diagnosed as a ganglioneuroma.