Surgical staging in patients with ovarian tumors of low malignant potential
Surgical staging in patients with ovarian tumors of low malignant potential
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DOI：
10.1016/s0029-7844(02)02171-3
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发表时间：
2002-10-01
影响因子：
7.2
通讯作者：
Maxwell, GL
中科院分区：
文献类型：
--
作者：
Winter, WE;Kucera, PR;Maxwell, GL
目的：为了比较卵巢肿瘤的低恶性潜能的患者的结果，谁有完整的手术分期与那些谁是unstaged，以确定是否复发率或生存率受到手术staging.METHODS的影响：一个回顾性的图表审查进行了93个连续的患者谁有手术的组织学证实的低恶性潜能的肿瘤在1979年和1997年之间。确定了两个患者队列：具有经典手术分期的患者（n = 48）与未分期的患者（n = 45）。结果：早期（I或H）疾病被诊断为31 48例手术分期和42 45例未分期的患者（P = 0.001）。在17%的患者中，他们的分期在手术分期的基础上进行了升级，因为这些病例中只有6%的病例（48例分期患者中的3例）涉及腹膜后。在研究期间，其他8名患者的冷冻切片诊断为低恶性潜能卵巢肿瘤，最终诊断为浸润性癌。分期和未分期低恶性潜能组均有3例复发和2例死亡。平均随访时间为6.5 +/- 4.2年，两组相似。总体5年生存率约为93%for all stages.CONCLUSION：生存率和复发率之间没有显着差异分期和未分期的患者谁有手术的低恶性潜力的卵巢肿瘤。(C)2002年由美国妇产科医师学会。
OBJECTIVE: To compare the outcomes of patients with ovarian tumors of low malignant potential who had complete surgical staging with those who were unstaged to determine whether the rate of recurrence or survival was affected by surgical staging.METHODS: A retrospective chart review was performed on 93 consecutive patients who had surgery for histologically confirmed tumors of low malignant potential between 1979 and 1997. Two cohorts of patients were identified: patients who had classic surgical staging (n = 48) versus those who were not staged (n = 45). Outcome data were recorded for patients and compared between the two groups.RESULTS: Early stage (I or H) disease was diagnosed in 31 of 48 patients who had surgical staging and 42 of 45 patients who were not staged (P =.001). In 17% of patients their stage was upgraded on the basis of surgical staging, as a result of retroperitoneal involvement in only 6% of those cases (three of 48 staged patients). During the study interval, the frozen section diagnosis of low malignant potential tumor of the ovary was changed to a final diagnosis of invasive cancer in eight other patients. There were three recurrences and two deaths in both the staged and unstaged low malignant potential groups. The average duration of follow-up was 6.5 +/- 4.2 years and was similar in the two groups. Overall 5-year survival was approximately 93% for all stages.CONCLUSION: Survival and recurrence rates were not significantly different between staged and unstaged patients who had surgery for low malignant potential tumors of the ovary. (C) 2002 by The American College of Obstetricians and Gynecologists.