Recovery of microalgal biomass and metabolites: process options and economics.
Recovery of microalgal biomass and metabolites: process options and economics.
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DOI：
10.1016/s0734-9750(02)00050-2
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发表时间：
2003
影响因子：
16
通讯作者：
E. Molina Grima;E. Belarbi;F. G. Acién Fernández;A. Robles Medina;Y. Chisti
中科院分区：
文献类型：
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作者：
E. Molina Grima;E. Belarbi;F. G. Acién Fernández;A. Robles Medina;Y. Chisti
细胞内微藻代谢物的商业生产需要以下：（1）适当微藻生物质的大规模单菌培养生产;（2）从相对稀释的培养液中回收生物质;（3）从生物质中提取代谢物;和（4）纯化粗提取物。本文综述了生物质和细胞内代谢产物的回收方法。以二十碳五烯酸（EPA）回收为代表，讨论了光生物反应器中微藻单菌生产和下游代谢产物回收的经济性。
Commercial production of intracellular microalgal metabolites requires the following: (1) large-scale monoseptic production of the appropriate microalgal biomass; (2) recovery of the biomass from a relatively dilute broth; (3) extraction of the metabolite from the biomass; and (4) purification of the crude extract. This review examines the options available for recovery of the biomass and the intracellular metabolites from the biomass. Economics of monoseptic production of microalgae in photobioreactors and the downstream recovery of metabolites are discussed using eicosapentaenoic acid (EPA) recovery as a representative case study.