Infantile disseminated visceral giant cell arteritis presenting as sudden infant death
Infantile disseminated visceral giant cell arteritis presenting as sudden infant death
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婴儿播散性内脏巨细胞动脉炎表现为婴儿猝死
DOI：
10.1046/j.1440-1827.1999.00851.x
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发表时间：
1999
期刊：
影响因子：
--
通讯作者：
E. Mark
中科院分区：
文献类型：
--
作者：
Y. Kagata;O. Matsubara;S. Ogata;J. Lie;E. Mark
罕见的临床病理实体'播散性内脏巨细胞动脉炎'（DVGCA）首次于1978年描述。其特征在于广泛的小血管巨细胞血管炎和血管外肉芽肿。报告了一名正常和健康的7个月大男孩意外出现婴儿猝死综合征（SIDS）。尸检组织学检查显示主动脉、颈总动脉、冠状动脉、肺动脉、腹腔动脉、肠系膜动脉和髂总动脉存在巨细胞血管炎。气管壁和肝脏也有肉芽肿。据我们所知，这是第一例记录在案的DVGCA发生在12个月以下的婴儿。本文回顾了有关DVGCA的文献，并讨论了鉴别诊断。
The rare clinicopathological entity ‘disseminated visceral giant cell arteritis’ (DVGCA) was first described in 1978. It is characterized by widespread small‐vessel giant cell angitis and extravascular granulomas. A normal and healthy 7‐month‐old boy who presented unexpectedly with sudden infant death syndrome (SIDS) is reported. Histological examination at autopsy revealed giant cell angitis of the aorta, common carotid, coronary, pulmonary, celiac, mesenteric and common iliac arteries. There were also granulomas in the tracheal wall and liver. To our knowledge, this is the first documented case of DVGCA occurring in an infant younger than 12 months of age. A review of the literature on DVGCA is presented in this report, and the differential diagnosis is discussed.