Heterotopic ossification in burns: Our experience and literature reviews
Heterotopic ossification in burns: Our experience and literature reviews
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DOI：
10.1016/j.burns.2008.03.002
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发表时间：
2009-09-01
期刊：
影响因子：
2.7
通讯作者：
Yang, Shih-Yi
中科院分区：
文献类型：
--
作者：
Chen, Hung-Chang;Yang, Jui-Yung;Yang, Shih-Yi
目的：异位骨化（HO）是一种罕见但引人注目的烧伤并发症。在本文中，进行了一项回顾性研究来评估我们的 HO 治疗和结果。并查阅相关文献，寻找烧伤后HO患者预防和治疗的新进展。材料与方法：在林口长庚医院进行回顾性研究。收集2000年6月至2007年9月期间在我院接受手术的12例烧伤后HO患者，数据以平均值表示。结果：患者性别分布为男性10例，女性2例。平均年龄为 43 岁（范围：30-59 岁）。烧伤原因为火焰烧伤（75%）、烫伤（8%）、接触烧伤（8%）和高压电烧伤（8%）。平均 TBSA 为 39%（范围为 8-90%）。 12 名患者中的 9 名 (75%) 住进重症监护病房 (ICU)，6 名患者 (50%) 接受机械呼吸机支持。平均 ICU 住院时间为 82 天（范围为 26-240 天）。肘部是最常受影响的关节（92%）。手术时所有肘部的手术结果都是可以接受的。手术前的平均 ROM 为 31 度（范围：0-75 度）。术后平均 ROM 为 99 度（范围为 70-115 度）；平均增益为 68 度（范围为 35-115 度）。 1 名（8%）患者术后复发 HO。平均门诊随访时间为 14.6 个月（范围：1-40 个月）。我们烧伤中心HO的发生率为0.15%。结论：虽然烧伤后HO并不常见，但医生应牢记其并发症。当烧伤患者抱怨关节活动度降低或“锁定征”时，需要进行 X 射线检查以排除 HO。当 HO 诊断确诊后，手术是首选治疗方法。 (C) 2008 Elsevier Ltd 和 ISBI。版权所有。
Purposes: Heterotopic ossification (HO) is an uncommon, but high profile complication of burns. In this paper, a retrospective study was undertaken to evaluate our treatment and results of HO. Relevant literature was also reviewed to search for new advances in prevention and management for patients with HO after burns.Materials and methods: A retrospective study was undertaken in Chang Gung Memorial Hospital, Linkou. We collected 12 patients who suffered from HO after burn and received operation in our hospital between June 2000 and September 2007. The data was expressed as mean.Results: Patients' gender distribution was 10 males and 2 females. The mean age was 43 years old (range, 30-59). Causes of burn were flame burn (75%), scald burn (8%), contact burn (8%), and high-voltage electrical burn (8%). Mean TBSA was 39% (range, 8-90%). Nine of 12 patients (75%) were admitted to intensive care unit (ICU) and 6 (50%) received mechanical ventilator support. The mean ICU stay was 82 days (range, 26-240 days). The elbow was the most commonly affected joint (92%). The outcome of surgery was acceptable in all elbows at the time of surgery. The mean ROMs before surgery were 31 degrees (range, 0-75 degrees). The mean ROMs after surgery were 99 degrees (range, 70-115 degrees); mean gain was 68 degrees (range, 35-115 degrees). One (8%) patients had recurrent HO after operation. The mean outpatient department follow-up time was 14.6 months (range, 1-40 months). The incidence of HO in our burn center is 0.15%.Conclusion: Although HO after burn is uncommon, physicians should keep the complication in mind. When burn patients complain decreased ROM or "locking sign" in their joints, X-ray examination is indicated to rule out HO. Surgery is the treatment of choice when the diagnosis of HO is confirmed. (C) 2008 Elsevier Ltd and ISBI. All rights reserved.