Electrochemically controlled release of α,β,γ,δ-tetrakis(4-N-methylpyridyl)porphine from layer-by-layer thin films
Electrochemically controlled release of α,β,γ,δ-tetrakis(4-N-methylpyridyl)porphine from layer-by-layer thin films
复制标题
DOI：
10.1016/j.jcis.2008.12.071
复制
发表时间：
2009-05-01
影响因子：
9.9
通讯作者：
Anzai, Jun-ichi
中科院分区：
文献类型：
--
作者：
Sato, Hiroshi;Takano, Yoichi;Anzai, Jun-ichi
研究了聚烯丙基胺盐酸盐(PAH)和聚丙烯酸(PAA)组成的层层组装薄膜中α，β，γ，β-四(4-N-甲基吡啶)卟啉(TMPyP)的电化学控制释放。在涂有TMPyP的PAH/PAA膜的玻碳电极上施加正电极电位(+1.2~+1.5V)可以提高TMPyP的释放速率，而较低的电极电位(0~+1.0V)对TMPyP的释放影响很小。在pH为7.4时，外加电位对释药速率的影响比在pH为8.0和9.0时更为显著。电化学促进TMPyP的释放是基于电极表面附近的局部pH变化，这是由于电解H2O引起的。(C)2009 Elsevier Inc.保留所有权利。
The release of alpha,beta,gamma,delta-tetrakis(4-N-methylpyridyl)porphyrin (TMPyP) from layer-by-layer assembled thin films composed of poly(allylamine hydrochloride) (PAH) and poly(acrylic acid) (PAA) was electrochemically controlled. The release rate of TMPyP was enhanced when a positive electrode potential (+1.2 to +1.5 V) was applied to the glassy carbon electrode on which TMPyP-loaded PAH/PAA film was coated, while the effect of lower electrode potentials (0 to +1.0 V) was negligibly small. The effect of applied potential on the release rate was more significant at pH 7.4 than in the solutions of pH 8.0 and 9.0. The electrochemically enhanced release of TMPyP was rationalized based on local pH change in the vicinity of the electrode surface, which was induced by electrolysis of H2O. (C) 2009 Elsevier Inc. All rights reserved.