Diagnosis of Latent Tuberculosis Infection
Diagnosis of Latent Tuberculosis Infection
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DOI：
10.1128/microbiolspec.tnmi7-0019-2016
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发表时间：
2017-02-01
影响因子：
3.7
通讯作者：
Reichman, Lee B.
中科院分区：
文献类型：
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作者：
Lardizabal, Alfred A.;Reichman, Lee B.
2015年，美国结核病（TB）发病率稳定在每10万人3.0人。这仍然是自记录开始以来的最低案件率。在全球一级，尽管结核病流行比以前估计的要大，但结核病死亡人数和发病率继续下降。对于低发病率国家和高发病率国家而言，要加速降低结核病发病率，实现消除结核病的目标，除了在全球范围内改善结核病护理外，还需要更加重视加强潜伏性结核病感染（LTBI）的检测和治疗系统。在这里，我们回顾结核菌素皮肤试验和γ干扰素释放测定目前可用于检测LTBI。
For 2015, tuberculosis (TB) incidence in the United States has plateaued at 3.0 per 100,000. This remains the lowest case rate since recording started. On the global level, although the TB epidemic is larger than previously estimated, TB deaths and incidence rate continue to fall. For both low and high incidence countries, accelerating the decline in TB incidence towards elimination goals requires that more emphasis be placed on strengthening systems for detection and treatment of latent TB infection (LTBI) in addition to improving TB care globally. Here, we review the tuberculin skin test and gamma interferon release assays currently available for the detection of LTBI.