CORRELATION OF THE 24-HOUR RADIOIODINE UPTAKE OF THE HUMAN THYROID GLAND WITH THE 6-HOUR AND 8-HOUR UPTAKES AND THE ACCUMULATION GRADIENT
CORRELATION OF THE 24-HOUR RADIOIODINE UPTAKE OF THE HUMAN THYROID GLAND WITH THE 6-HOUR AND 8-HOUR UPTAKES AND THE ACCUMULATION GRADIENT
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DOI：
10.1172/jci102444
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发表时间：
1951-01-01
影响因子：
15.9
通讯作者：
GREER, MA
中科院分区：
文献类型：
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作者：
GREER, MA
在甲状腺功能正常的人类受试者中研究了甲状腺的蓄积梯度、6小时和8小时摄取与24小时放射性I摄取的相关性。所有四个功能之间存在密切的相关性。如果用y表示24小时摄取量，用x表示各种其它函数，则可以构造出相对精确的公式，利用这些公式可以从任何其它函数计算出24小时摄取量，反之亦然。因此，y = 31.2x - 3.62x2 [±] 0.141y是蓄积梯度的公式，y = 1.67x[±] 0.129y是6小时摄取的公式，y = 1.43x[±] 0.134y是8小时摄取的公式。即使甲状腺受到外源性甲状腺激素的抑制，这些相关性仍然存在。这里提供的数据可能是有价值的甲状腺生理功能正常的受试者在未来的调查。这表明，在甲状腺功能亢进的受试者中，预期相关性要小得多。
The correlation of the accumulation gradient, 6-hour, and 8-hour uptake with the 24-hour uptake of radioactive I by the thyroid gland was investigated in euthyroid human subjects. A close correlation was found between all four functions. If y is taken to represent the 24-hour uptake and x the various other functions, relatively precise formulae can be constructed by means of which the 24-hour uptake can be calculated from any of the other functions and vice versa. Thus, y = 31.2x - 3.62x2 [plus or minus] 0.141y is the formula for the accumulation gradient, y = 1.67x[plus or minus] 0.129y is the formula for the 6-hour uptake, and y = 1.43x[plus or minus] 0.134y is the formula for the 8-hour uptake. These correlations hold even when the thyroid gland is suppressed by exogenous thyroid hormone. The data presented here may be of value in future investigations of thyroid physiology in euthyroid subjects. It is suggested that far less correlation would be expected in thyrotoxic subjects.