Autologous and heterologous blood transfusion in head and neck cancer surgery
Autologous and heterologous blood transfusion in head and neck cancer surgery
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DOI：
10.1001/archotol.125.8.864
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发表时间：
1999-08-01
影响因子：
--
通讯作者：
Terris, DJ
中科院分区：
文献类型：
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作者：
Moir, MS;Samy, RN;Terris, DJ
目的：确定自体血的使用是否能改善与围手术期输血相关的癌症复发风险增加。设计：回顾性病历回顾。设置：三级护理医院。患者：从1989年1月1日至12月31日，在一所大学医院接受手术治疗的165例连续的II期至IV期头颈部鳞状细胞癌患者，1994.主要结果测量：我们评估了围手术期自体和异体输血以及其他10个变量对复发的影响。单因素和多因素分析used.Results：异体血受体有59%的复发率，而那些接受自体血或没有输血的复发率分别为33%和35%。多因素分析显示，以下4个变量与复发有统计学意义：既往治疗（P
Objective: To determine if the use of autologous blood ameliorates the increased risk for cancer recurrence that has been associated with perioperative blood transfusion.Design: Retrospective medical record review.Setting: Tertiary care hospital.Patients: One hundred sixty-five consecutive patients with stages II to IV squamous cell carcinoma of the head and neck treated surgically at a university hospital from January 1, 1989, through December 31, 1994.Main Outcome Measures: We evaluated the impact of perioperative autologous and heterologous blood transfusion and 10 other variables on recurrence. Univariate and multivariate analyses were used.Results: Heterologous blood recipients had a 59% recurrence rate, whereas those who had received autologous blood or no transfusion had recurrence rates of 33% and 35%, respectively. The following 4 variables had a statistically significant association with recurrence by multivariate analysis: previous treatment of current malignancy (P