Spotlight on avian pathology: the importance of recombinant vector platform technologies in poultry vaccination
Spotlight on avian pathology: the importance of recombinant vector platform technologies in poultry vaccination
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DOI：
10.1080/03079457.2021.1875624
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发表时间：
2021-02-09
期刊：
影响因子：
2.8
通讯作者：
Francis, Michael James
中科院分区：
文献类型：
--
作者：
Francis, Michael James
新型载体疫苗（病毒、细菌和顶复体）的使用可对家禽疾病的控制产生重大影响。它们提供了具有成本效益、方便和有效的大规模疫苗递送手段，并具有开启抗体和细胞介导的免疫的能力。此外，最近的病毒载体构建体使农民能够通过单次卵内施用接种针对多达三种重要病原体的疫苗。随着技术的发展，这种疫苗接种手段很可能会得到进一步利用，并将在未来控制现有和新出现的家禽疾病方面发挥关键作用。
The use of novel vector vaccines (viral, bacterial and apicomplexan) can have a significant impact on the control of poultry disease. They offer a cost effective, convenient and effective means of mass vaccine delivery combined with the ability to switch on both antibody and cell-mediated immunity. In addition, recent viral vector constructs have enabled farmers to vaccinate against up to three important pathogens with a single in ovo administration. As the technology develops, it is likely that this means of vaccine administration will be utilized further and it will play a key role in the control of both existing and new emerging diseases of poultry in the future.