A newly identified tyrosine kinase is preferentially expressed in the gastrointestinal tract.
A newly identified tyrosine kinase is preferentially expressed in the gastrointestinal tract.
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新发现的酪氨酸激酶优先在胃肠道中表达。
DOI：
10.1016/0167-4889(94)90260-7
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
Avigan,MI
中科院分区：
文献类型：
--
作者：
Sunitha,I;Avigan,MI
我们从大鼠肠道mRNA中克隆出一种新的蛋白酪氨酸激酶，该蛋白在肠细胞中选择性高水平表达，但在其他多种上皮和非上皮器官中表达水平较低或不显著。胃肠相关激酶（GASK） mRNA在胃、小肠和结肠中呈高水平表达。GASK可能在胃肠道的生长、分化和/或发育中起重要作用。
We have identified a novel protein tyrosine kinase, cloned from rat intestinal mRNA, which is selectively expressed at high levels in intestinal cells, but is expressed at low or insignificant levels in a variety of other epithelial and non-epithelial organs. Gastrointestinal associated kinase (GASK) mRNA is present at high levels in stomach, small intestine and colon. GASK may play an important role in the growth, differentiation and/or development of the gastrointestinal tract.