Incidence of nonarteritic anterior ischemic optic neuropathy in adult Chinese: The Beijing Eye Study
Incidence of nonarteritic anterior ischemic optic neuropathy in adult Chinese: The Beijing Eye Study
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DOI：
10.1177/112067210701700335
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发表时间：
2007-05-01
影响因子：
1.7
通讯作者：
Jonas, J. B.
中科院分区：
文献类型：
--
作者：
Xu, L.;Wang, Y.;Jonas, J. B.
目的。旨在确定中国成年人群中非动脉炎性前部缺血性视神经病变 (NAION) 引起的视神经损伤的发生率。方法。北京眼科研究是一项以人群为基础的纵向研究，2006 年纳入了 4439 名受试者（40 岁以上），2006 年又重复了一次。在后续检查中，有 3169 名受试者（71.4%）参与。评估光学、光盘照片。事件性 NAION 的诊断标准是随访检查中视盘小、节段苍白、视网膜神经纤维层和视野丧失，基线时视神经乳头外观正常。 结果。在一只眼睛中发现新的 NAION，发病率为每 5 年 0.03 +/- 0.03%（平均标准误差）（95% 置信区间：-0.03, 0.09），或每年约 1:16,000 名受试者。结论。 5年内，每3200名成年中国人中就有1人会出现新的NAION，即每年1:16,000名成年中国人中可能会出现新的NAION。
PURPOSE. To determine the incidence of optic nerve damage due to nonarteritic anterior ischemic optic neuropathy (NAION) in the adult Chinese population.METHODS. The Beijing Eye Study, a population-based, longitudinal study which included 4439 subjects (age 40+ years) in 2006, was repeated in 2006. In the follow-up examination, 3169 (71.4%) subjects participated. Optic,disc photographs were assessed. Diagnostic criteria for incident NAION were a small optic disc, segmental pallor, and loss of retinal nerve fiber layer and visual field in the follow-up examination, with a normal optic nerve head appearance at baseline.RESULTS. New NAION was found in one eye, with an incidence rate of 0.03 +/- 0.03% per 5 years (mean standard error) (95% confidence interval: -0.03, 0.09), or about 1:16,000 subjects per year.CONCLUSIONS. Within a 5-year period, new NAION may develop in 1 out of 3200 adult Chinese, or 1:16,000 adult Chinese per year.