Ultrasound-guided microfoam sclerotherapy with polidocanol for symptomatic giant hepatic cyst: Initial experience
Ultrasound-guided microfoam sclerotherapy with polidocanol for symptomatic giant hepatic cyst: Initial experience
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DOI：
10.1111/hepr.13202
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发表时间：
2018-11-01
影响因子：
4.2
通讯作者：
Seno，Hiroshi
中科院分区：
文献类型：
--
作者：
Eso，Yuji;Furuta，Akihiro;Seno，Hiroshi
目的对于有症状的巨大肝囊肿，需要适当的治疗来缓解症状。乙醇、盐酸米诺环素和油酸乙醇胺通常用于超声（US）引导的硬化治疗。但液体硬化剂可与囊肿内残留液体混合，降低其硬化效果。我们进行了US引导下的微泡沫硬化治疗使用聚多卡醇为三名patients.MethodsBetween 2016年5月和2017年3月，三名女性患者有症状的巨大肝囊肿被转介到我们的医院，并评估其疗效和安全性。结果3例肝囊肿最大直径分别为92 × 89 × 86 mm、155 × 119 × 140 mm和223 × 195 × 123 mm。所有患者均通过8.5 Fr猪尾导管成功给予聚多卡醇微泡沫。根据病例1、2和3的初始囊肿体积，分别进行1、2和3次微泡沫硬化治疗。治疗后3个月囊肿体积平均缩小率为90.1%（85.5-98.9%），6个月为96.3%（91.9-99.9%），9个月为99.5%（99.1-99.9%）。结论超声引导下使用聚多卡醇微泡沫硬化剂治疗有症状的巨大肝囊肿是一种安全有效的方法。
AimIn cases of symptomatic giant hepatic cysts, appropriate treatment is required to relieve symptoms. Ethanol, minocycline hydrochloride, and ethanolamine oleate have been conventionally used for ultrasound (US)‐guided sclerotherapy. However, liquid sclerosing agents could mix with the residual fluid in the cyst and reduce their sclerotic effects. We carried out US‐guided microfoam sclerotherapy using polidocanol for three patients and evaluated its efficacy and safety.MethodsBetween May 2016 and March 2017, three female patients with symptomatic giant hepatic cysts were referred to our hospital. All of them were prospectively included in this study.ResultsThe maximum diameters of the hepatic cysts in the three patients were 92 × 89 × 86 mm, 155 × 119 × 140 mm, and 223 × 195 × 123 mm, respectively. Polidocanol microfoam was successfully administered through an 8.5‐Fr pigtail catheter for all patients. One, two, and three microfoam sclerotherapy sessions were undertaken according to the initial cyst volume for cases 1, 2, and 3, respectively. The mean reduction rates of the cyst volume were 90.1% (85.5–98.9%) at 3 months, 96.3% (91.9–99.9%) at 6 months, and 99.5% (99.1–99.9%) at 9 months after treatment. No significant treatment‐induced adverse effects were observed.ConclusionUltrasound‐guided microfoam sclerotherapy using polidocanol could be an effective and safe method for the treatment of symptomatic giant liver cysts.