P-wave Variability and Atrial Fibrillation.
P-wave Variability and Atrial Fibrillation.
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DOI：
10.1038/srep26799
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发表时间：
2016-05-26
影响因子：
4.6
通讯作者：
Boriani G
中科院分区：
文献类型：
--
作者：
Censi F;Corazza I;Reggiani E;Calcagnini G;Mattei E;Triventi M;Boriani G
P波模板分析已被广泛用于提取房颤（AF）危险分层指标。本文旨在评估分析房颤患者P波变异性随时间变化的潜力。从P波模板中提取的P波特征以及P波变异性的新指标已在持续性AF患者人群中进行了估计，并与从对照受试者中提取的P波特征进行了比较。我们使用三种算法量化P波随时间的变化，并提取了三个新的指数：一个基于P波之间的互相关系数（互相关指数，CCI），一个与P波振幅的变化相关（振幅色散指数，ADI），一个对P波之间的相移敏感（翘曲指数，WI）。与AF患者相比，对照组的P波持续时间较短，碎片和变异性较少。CCI敏感性最高（97.3%），特异性最好（95%）。
The analysis of P-wave template has been widely used to extract indices of Atrial Fibrillation (AF) risk stratification. The aim of this paper was to assess the potential of the analysis of the P-wave variability over time in patients suffering from atrial fibrillation. P-wave features extracted from P-wave template together with novel indices of P-wave variability have been estimated in a population of patients suffering from persistent AF and compared to those extracted from control subjects. We quantify the P-wave variability over time using three algorithms and we extracted three novel indices: one based on the cross-correlation coefficients among the P-waves (Cross-Correlation Index, CCI), one associated to variation in amplitude of the P-waves (Amplitude Dispersion Index, ADI), one sensible to the phase shift among P-waves (Warping Index, WI). The control group resulted to be characterized by shorter P-wave duration and by a less amount of fragmentation and variability, respect to AF patients. The parameter CCI shows the highest sensitivity (97.3%) and a good specificity (95%).