Evaluation of permeance in peritoneal dialysis.
Evaluation of permeance in peritoneal dialysis.
复制标题
腹膜透析渗透性的评估。
DOI：
10.3109/08860227809079322
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发表时间：
1978
期刊：
影响因子：
--
通讯作者：
K. Nolph
中科院分区：
文献类型：
--
作者：
F. Villarroel;R. Popovich;K. Nolph
腹膜透析中渗透性的评价。根据最少数量的实验测量值，建立了计算渗透率的关系。渗透率是有效腹膜面积乘以其传质系数的乘积。这些关系用于在透析液中加入和不加入硝普钠（一种直接血管扩张剂）的情况下获得的临床数据。硝普钠使BUN的渗透性增加34%，使肌酐和菊粉的渗透性增加约100%。在50分钟交换方案中，清除率的等效增加为24、60和83%。在几次长时间交换中每10分钟获得的标准化连续浓度数据与支持该方法充分性的计算值一致。给出了一个计算前一次透析液交换后剩余透析液量的表达式。计算值范围为200至500 ml。
Evaluation of permeance in peritoneal dialysis. Relations were developed to calculate permeance based on a minimum number of experimental measurements. Permeance is the product of the effective peritoneal area times its mass transfer coefficient. The relations were used on clinical data obtained with and without nitroprusside, a direct vasodilator, added to the dialysate. Nitroprusside increased permeance 34% for BUN and about 100% for creatinine and inulin. The equivalent increase in clearance in a 50 minute exchange protocol would be 24, 60, and 83%. Normalized consecutive concentration data obtained every ten minutes in several long exchanges agree well with calculated values supporting the adequacy of the approach. An expression is also given to calculate the residual dialysate volume left from the previous dialysate exchange. The values calculated ranged from 200 to 500 ml.