From DNA Nanotechnology to Material Systems Engineering
From DNA Nanotechnology to Material Systems Engineering
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DOI：
10.1002/adma.201806294
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发表时间：
2019-06-01
影响因子：
29.4
通讯作者：
Niemeyer, Christof M.
中科院分区：
文献类型：
--
作者：
Hu, Yong;Niemeyer, Christof M.
在过去的35年里，DNA纳米技术已经发展成为一个高度创新和充满活力的研究领域，在化学，材料科学，生物技术和纳米技术的界面。在这里，一个简短的总结，在DNA纳米技术的各个子学科的研究状态，范围从纯粹的“结构DNA纳米技术”的蛋白质-DNA组件，基于纳米粒子的DNA材料，DNA聚合物的DNA表面技术。调查显示，这些分支学科越来越紧密地联系在一起，并表明这种整合对于启动下一阶段的发展至关重要。随着微流体、机器人和数据驱动科学中基于机器的方法的越来越多的实施，DNA材料系统将出现，它们可能适合于传感器技术、光子学、技术系统和生物体之间的接口或仿生制造过程中的应用。
In the past 35 years, DNA nanotechnology has grown to a highly innovative and vibrant field of research at the interface of chemistry, materials science, biotechnology, and nanotechnology. Herein, a short summary of the state of research in various subdisciplines of DNA nanotechnology, ranging from pure "structural DNA nanotechnology" over protein-DNA assemblies, nanoparticle-based DNA materials, and DNA polymers to DNA surface technology is given. The survey shows that these subdisciplines are growing ever closer together and suggests that this integration is essential in order to initiate the next phase of development. With the increasing implementation of machine-based approaches in microfluidics, robotics, and data-driven science, DNA-material systems will emerge that could be suitable for applications in sensor technology, photonics, as interfaces between technical systems and living organisms, or for biomimetic fabrication processes.