Photoimmunology

Photoimmunology
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DOI:
10.1016/j.det.2014.03.005
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发表时间:
2014-07-01
影响因子:
2.4
通讯作者:
Xu, Hui
Xu, Hui
中科院分区:
医学2区
文献类型:
--
作者:
Elmets, Craig A.;Cala, Cather M.;Xu, Hui

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研究紫外线辐射对免疫系统的生物效应的学科称为光免疫学。光免疫学是从了解免疫系统在皮肤癌发展中的作用以及为什么免疫抑制的器官移植受者患皮肤肿瘤的风险大大增加的兴趣发展而来的。除了有助于了解非黑色素瘤皮肤癌的发病机制外,获得的有关紫外线辐射暴露的免疫学效应的知识还有助于了解其在其他光皮肤病发病机制中的作用。
The discipline that investigates the biologic effects of ultraviolet radiation on the immune system is called photoimmunology. Photoimmunology evolved from an interest in understanding the role of the immune system in skin cancer development and why immunosuppressed organ transplant recipients are at a greatly increased risk for cutaneous neoplasms. In addition to contributing to an understanding of the pathogenesis of nonmelanoma skin cancer, the knowledge acquired about the immunologic effects of ultraviolet radiation exposure has provided an understanding of its role in the pathogenesis of other photodermatologic diseases.