HIV detection by an emergency department HIV screening program during a regional outbreak among people who inject drugs.
HIV detection by an emergency department HIV screening program during a regional outbreak among people who inject drugs.
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DOI：
10.1371/journal.pone.0251756
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发表时间：
2021
期刊：
影响因子：
3.7
通讯作者：
Lyons MS
中科院分区：
文献类型：
--
作者：
Faryar KA;Ancona RM;Reau Z;Lyss SB;Braun RS;Rademaker T;Sickles RK;Lyons MS
自2015年以来，美国发生了多起注射毒品者（PWID）中的艾滋病毒疫情。急诊科（ED），公认为艾滋病毒筛查的重要场所，可能发挥独特的作用，在确定未确诊的艾滋病毒感染者之间的PWID，谁经常出现注射毒品使用（IDU）的并发症。我们的目标是描述艾滋病毒诊断的变化之间的PWID检测到的艾德艾滋病毒筛查计划，并估计该计划的贡献，艾滋病毒诊断之间的PWID县范围内出现的区域性艾滋病毒爆发。这是一项回顾性研究，对来自城市安全网艾德的HIV筛查项目的电子查询临床记录及其周边县俄亥俄州汉密尔顿县的公开HIV监测数据进行了回顾性研究。结果包括艾滋病毒诊断数量的变化以及艾德在2014-2018年期间对全县病例识别、总体和PWID的贡献。在2014-2018年期间，艾德计划每年诊断的艾滋病毒总数从20例增加到42例，PWID从1例增加到18例。我们估计，艾德占该县艾滋病毒诊断的18%，占PWID诊断的22%。艾德计划在全国范围内的PWID中贡献了五分之一的新艾滋病毒诊断，进一步说明了艾德艾滋病毒筛查计划在识别未确诊的艾滋病毒感染方面的重要性。在注射吸毒者增加的地区，急诊室的艾滋病毒筛查可以提供艾滋病毒诊断在PWID中增加的早期迹象，并在艾滋病毒爆发期间大大有助于病例发现。
Multiple HIV outbreaks among persons who inject drugs (PWID) have occurred in the US since 2015. Emergency departments (EDs), recognized as essential venues for HIV screening, may play a unique role in identifying undiagnosed HIV among PWID, who frequently present for complications of injection drug use (IDU). Our objective was to describe changes in HIV diagnoses among PWID detected by an ED HIV screening program and estimate the program’s contribution to HIV diagnoses among PWID county-wide during the emergence of a regional HIV outbreak. This was a retrospective study of electronically queried clinical records from an urban, safety-net ED’s HIV screening program and publicly available HIV surveillance data for its surrounding county, Hamilton County, Ohio. Outcomes included the change in number of HIV diagnoses and the ED’s contribution to case identification county-wide, overall and for PWID during 2014–2018. During 2014–2018, the annual number of HIV diagnoses made by the ED program increased from 20 to 42 overall, and from 1 to 18 for PWID. We estimated that the ED contributed 18% of HIV diagnoses in the county and 22% of diagnoses among PWID. The ED program contributed 1 in 5 new HIV diagnoses among PWID county-wide, further illustrating the importance of ED HIV screening programs in identifying undiagnosed HIV infections. In areas experiencing increasing IDU, HIV screening in EDs can provide an early indication of increasing HIV diagnoses among PWID and can substantially contribute to case-finding during an HIV outbreak.
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影响因子：
168.9
作者：
Nelson, Paul K.;Mathers, Bradley M.;Cowie, Benjamin;Hagan, Holly;Des Jarlais, Don;Horyniak, Danielle;Degenhardt, Louisa
通讯作者：
Degenhardt, Louisa
影响因子：
33.9
作者：
Golden, Matthew R.;Lechtenberg, Richard;Buskin, Susan E.
通讯作者：
Buskin, Susan E.
影响因子：
2
作者：
Nambiar, Dhanya;Spelman, Tim;Dietze, Paul
通讯作者：
Dietze, Paul
影响因子：
2.8
作者：
Di Rico, Rehana;Nambiar, Dhanya;Dietze, Paul
通讯作者：
Dietze, Paul
影响因子：
4.2
作者：
Marks LR;Nolan NS;Jiang L;Muthulingam D;Liang SY;Durkin MJ
通讯作者：
Durkin MJ