Forty minutes of experience increase the weight and RNA content of cerebral cortex in periadolescent rats.
Forty minutes of experience increase the weight and RNA content of cerebral cortex in periadolescent rats.
复制标题
四十分钟的体验会增加青春期大鼠的体重和大脑皮层的 RNA 含量。
DOI：
10.1002/dev.420190604
复制
发表时间：
1986
影响因子：
2.2
通讯作者：
Eterovic,VA
中科院分区：
文献类型：
--
作者：
Ferchmin,PA;Eterovic,VA
这项工作的目的是确定暴露于环境复杂性（EC）的最短时间，这将产生大脑重量或RNA含量的可测量变化。这一时期随着受试者的年龄而变化。在3个月大的年轻成年大鼠中，暴露于EC 4天后，枕皮质RNA浓度高于处于贫困条件（IC）的窝鼠水平。皮质重量未受影响。每天7小时或1小时的EC暴露在大鼠的EC和IC中没有显著差异。在青春期大鼠中，30至40天大鼠，每天1小时的富集4天增加了枕皮质的重量及其RNA含量。每天暴露7或24小时也会产生类似的结果。在另一项实验中，青春期大鼠每天暴露于EC 1小时甚至10分钟，持续4天，总皮质重量和RNA含量增加。因此，青春期前后的大鼠大脑显示出非常高的可塑性。这些非常短的接触时间与简单的正式培训的学习时间相当。
The goal of this work was to determine the shortest period of exposure to environmental complexity (EC) that would produce measurable changes in brain weight or RNA content. This period varied with the age of subjects. In young adult rats, 3 months old, 4 days of exposure to EC increased the RNA concentration in the occipital cortex above the level of littermates kept in impoverished condition (IC). Cortical weight was not affected. Seven or one daily hrs of exposure to EC did not produce significant differences between rats in EC and IC. In periadolescent rats, 30‐ to 40‐day‐old, 1 daily hr of enrichment for 4 days increased both the weight of occipital cortex and its RNA content. Exposures of 7 or 24 hrs/day produced similar results. In another experiment with periadolescent rats 1 hr or even 10 min of exposure to EC per day, for 4 days, increased total cortical weight and RNA content. Thus, periadolescent rat brain display remarkably high plasticity. These very short exposure periods are comparable to the duration of learning sessions in simple formal trainings.