Ligand-Free Pd-Catalyzed Carbonylative Cross-Coupling Reactions under Atmospheric Pressure of Carbon Monoxide: Synthesis of Aryl Ketones and Heteroaromatic Ketones
Ligand-Free Pd-Catalyzed Carbonylative Cross-Coupling Reactions under Atmospheric Pressure of Carbon Monoxide: Synthesis of Aryl Ketones and Heteroaromatic Ketones
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DOI：
10.1002/ejoc.201001685
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发表时间：
2011-05-01
影响因子：
2.8
通讯作者：
Xue, Jijun
中科院分区：
文献类型：
--
作者：
Li, Hongling;Yang, Min;Xue, Jijun
首次在一氧化碳常压下以Pd-2(dba)(3)为无配体催化剂催化硼酸与芳基碘化物的羰基化Suzuki交叉偶联反应。在温和的反应条件下，多种芳基/杂芳基碘化物和芳基/杂芳基硼酸选择性偶联，以低催化剂负载量（0.05至2摩尔％）以良好至优异的收率提供相应的二芳基酮。此外，催化剂还可以回收利用。
The carbonylative Suzuki cross-coupling reactions of boronic acids with aryl iodides catalyzed by Pd-2(dba)(3) as a ligand-free catalyst under atmospheric pressure of carbon monoxide has been firstly developed. Under mild reaction conditions, a broad range of aryl/heteroaryl iodides and aryl/heteroaryl boronic acids were selectively coupled to afford the corresponding diaryl ketones in good to excellent yields at low catalyst loadings (0.05 to 2 mol-%). Moreover, the catalyst can also be recycled.