Nutritional status of children admitted to hospital with different diseases and its relationship to outcome in The Gambia, West Africa
Nutritional status of children admitted to hospital with different diseases and its relationship to outcome in The Gambia, West Africa
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DOI：
10.1046/j.1365-3156.1998.00283.x
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发表时间：
1998-08-01
影响因子：
3.3
通讯作者：
Greenwood, BM
中科院分区：
文献类型：
--
作者：
Man, WDC;Weber, M;Greenwood, BM
使用冈比亚两个儿科病房的入院记录来探讨入院体重与不同疾病之间的关系。总共对 13579 名住院儿童进行了分析。为了进行比较，我们从多项健康受试者调查中招募了 7399 名儿童，为健康的冈比亚儿童提供人体测量值。与对照儿童相比，疟疾（年龄体重z值：-1.602）、脑型疟疾（-1.547）、输血性疟疾贫血（-1.764）、肺炎（-1.735）、脑膜炎（-1.362）、胃肠炎（-2.497）和营养不良（-3.786）的平均入院体重较低。患有细支气管炎的儿童与对照组儿童的年龄体重没有显着差异。记录入院结果并与入院时的体重相关。在所有疾病类别中，除细支气管炎外，死亡率随着入院体重的降低而增加。就所有疾病而言，年龄别体重 z 得分高于 -2 标准差 (SD) 3 的儿童的病死率为 7.2%，-2 至 -3 标准差 (SD) 之间的儿童病死率为 9.3%，-3 至 -4 标准差 (SD) 之间的儿童病死率为 15.6%，年龄别体重 SD z 得分低于 -4 的儿童病死率为 22.7%。营养不良的儿童更容易感染发展中国家常见的几种传染病，营养干预措施以及标准治疗可能会改善结果。
Admission records from two paediatric units in The Gambia were used to explore the relationship between admission weight and different diseases. In total 13579 hospitalized children were analysed. For comparison, 7399 children were recruited from several surveys of well subjects to provide anthropometric values for healthy Gambian children. Compared to the control children, mean admission weights were lower for malaria (weight for age z-score: -1.602), cerebral malaria (-1.547), transfused malarial anaemia (-1.764), pneumonia (-1.735), meningitis (-1.362), gastro-enteritis (-2.497) and malnutrition (-3.786). Children with bronchiolitis did not have a significantly different weight for age than the controls. Outcome of the hospital admission was recorded and related to the weight on admission. In all disease categories the death rare rose with decreasing admission weight with the exception of bronchiolitis. For all diseases taken together, case fatality was 7.2% for children with 3 weight for age z-score above -2 Standard Deviations (SD), 9.3% between -2 and -3 SD, 15.6% between -3 and -4 SD and 22.7% for children with weight for age SD z-scores less than -4. Malnourished children are more susceptible to several infectious diseases frequently seen in developing countries and nutritional interventions, as well as standard treatment, may improve outcome.