Microwave-assisted rapid synthesis of poly(glycerol-sebacate) elastomers
Microwave-assisted rapid synthesis of poly(glycerol-sebacate) elastomers
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DOI：
10.1039/c3bm00157a
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发表时间：
2013-01-01
影响因子：
6.6
通讯作者：
Piskin, E.
中科院分区：
文献类型：
--
作者：
Aydin, H. M.;Salimi, K.;Piskin, E.
聚（甘油-癸二酸酯）（PGS）在十年前被引入作为软组织修复的潜在材料。文献中提出的所有共聚反应包括两阶段（预聚合和固化）合成，其中反应时间可长达数天。另一方面，这项研究提出了一种新的路线，消除了这些缺点，并能够通过微波辅助预聚合在几分钟内而不是几天内快速合成PGS弹性体。在第一预聚合步骤中不需要吹扫气体、催化剂或真空。固化阶段在150 ° C下进行4、8、16和24小时。发现这些PGS弹性体的甘油和癸二酸片段的玻璃化转变温度（T-g）和熔融温度（T-m1和T-m2）分别为-35.61 ℃、-15.82 ℃和61.70 ℃。发现杨氏模量和拉伸强度值分别为0.50 +/-0.02MPa和0.27 +/-0.06MPa。
Poly(glycerol-sebacate) (PGS) was introduced a decade ago as a potential material for soft tissue repair. All of the proposed copolymerization reactions in the literature include a two-stage (prepolymerization and curing) synthesis where the reaction times can take as long as several days. This study, on the other hand, proposes a new route that eliminates these disadvantages and enables a rapid synthesis of PGS elastomers via microwave-assisted prepolymerization in minutes instead of days. No purge gas, catalyst or vacuum is needed in the first prepolymerization step. The curing stage was carried out at 150 degrees C for 4, 8, 16, and 24 hours. The glass transition temperature (T-g) and melting temperatures for the glycerol and sebacic acid fragments (T-m1 and T-m2) of these PGS elastomers were found as -35.61 degrees C, -15.82 degrees C, and 61.70 degrees C, respectively. The Young's modulus and tensile strength values were found as 0.50 +/- 0.02 MPa and 0.27 +/- 0.06 MPa, respectively.