Investigations into the production and interconversion of phomoidrides A-D.
Investigations into the production and interconversion of phomoidrides A-D.
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DOI：
10.1021/ol015707k
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发表时间：
2001-04
期刊：
影响因子：
5.2
通讯作者：
P. Spencer;F. Agnelli;G. Sulikowski
中科院分区：
文献类型：
--
作者：
P. Spencer;F. Agnelli;G. Sulikowski
[结构：见正文]ATCC 74256的发酵分离和鉴定了拟豆蔻内酯A(CP-225,917)和拟豆蔻内酯B(CP-263,114)的C7异构体。我们建议将这些新的发酵产品命名为拟除虫菊酯C和D。PH对拟除虫菊酯A-D分布的影响研究表明，拟除虫菊酯B(CP-263,114)是第一次形成的次生代谢物，也是其余三种拟除虫菊酯的来源。
[structure: see text] Fermentation of ATCC 74256 led to the isolation and identification of C7 epimers of phomoidride A (CP-225,917) and phomoidride B (CP-263,114). We suggest the names phomoidrides C and D for these new fermentation products. Studies on the effect of pH on the distribution of phomoidrides A-D suggest phomoidride B (CP-263,114) is the first-formed secondary metabolite and the source of the remaining three phomoidrides.