Modulation of behavior by biogenic amines and peptides in the blue crab, Callinectes sapidus.
Modulation of behavior by biogenic amines and peptides in the blue crab, Callinectes sapidus.
复制标题
蓝蟹 Callinectes sapidus 中生物胺和肽对行为的调节。
DOI：
10.1007/bf00192421
复制
发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Derby,CD
中科院分区：
文献类型：
--
作者：
Wood,DE;Gleeson,RA;Derby,CD
以蓝蟹为模型系统，研究了潜在神经调节剂对自由行为动物的影响。我们感兴趣的是一些药物对蓝蟹三种节律行为的调节作用：雄蟹的求偶显示（CD）、侧游和后游。被测试的药物是proctolin、多巴胺、章鱼胺、血清素和去甲肾上腺素。注射每一种药物都会引起独特的姿势或肢体运动组合。这些实验显示了与CD行为相关的两个结果：注射多巴胺后显示与CD姿势相同的姿势；直泌素引起与CD相似的有节奏的腿部摆动。注射5 -羟色胺后，出现不同寻常的四肢屈伸和部分肢体运动。章鱼胺的注射导致体位对抗CD体位。这些药物的作用具有浓度和时间依赖性。注射多巴胺、章鱼胺或血清素产生的影响是季节性的，而proctolin的影响被证明是依赖于发育阶段的。定量分析的腿部摆动运动后，proctolin注射允许比较这些运动的自然发生的行为。
Using the blue crabCallinectes sapidusas a model system, we have investigated the effects of potential neuromodulators on freely behaving animals. Of interest is the modulatory effect of a number of drugs on three rhythmic behaviors of the blue crab: courtship display (CD) of the male crab, sideways swimming and backward swimming. The drugs tested were proctolin, dopamine, octopamine, serotonin, and norepinephrine. Injection of each drug elicited a unique posture or combination of limb movements. These experiments showed two results pertinent to CD behavior: A posture identical to the CD posture was displayed after dopamine injection; and rhythmic leg waving similar to CD was evoked by proctolin. An unusual combination of flexion and extension of all limbs and movements of some limbs occurred after serotonin injection. Injection of octopamine led to a posture antagonistic to CD posture. The effects of these drugs were concentration- and time-dependent. Injection of dopamine, octopamine, or serotonin produced effects that were seasonally-dependent, and the influence of proctolin proved to be dependent on developmental stage. Quantitative analysis of leg waving movements after proctolin injection allowed for comparison of these movements to naturally-occurring behavior.