Synthesis of Polyglycidol Hydrogel Films Crosslinked with Carboxyl-terminated Poly(ethylene glycol)
Synthesis of Polyglycidol Hydrogel Films Crosslinked with Carboxyl-terminated Poly(ethylene glycol)
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端羧基聚乙二醇交联聚缩水甘油水凝胶薄膜的合成
DOI：
10.1295/polymj.38.335
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发表时间：
2006
期刊：
影响因子：
2.8
通讯作者：
K. Yoshinaga
中科院分区：
文献类型：
--
作者：
Bong;J. Im;S. Baek;Jang;Maki Sigeta;K. Yoshinaga
为了在保持力学性能的同时大幅度提高水含量，采用不同分子量的端羧基聚乙二醇（PEG）作为低聚交联剂，制备了超支化聚缩水甘油（PGLD）水凝胶膜。测量了PEG交联PGLD水凝胶的溶胀和力学（拉伸）性能，并与以前的谷氨酸交联体系进行了比较。所得的PGLD膜表现出更高的凝胶分数和更大的溶胀能力，即使在低PEG浓度相比，那些交联与谷氨酸，可能是由于亲水性和长链效应的PEG交联剂的组合效应。在给定的（较低的）交联剂浓度下，PEG交联膜的杨氏模量和拉伸强度的值也高于谷氨酸。此外，PGLD水凝胶的溶胀和拉伸性能在很大程度上受交联剂浓度的影响。
With the attempt to largely increase the water content while keeping mechanical properties, hyperbranched polyglycidol (PGLD) hydrogel films were prepared using the oligomeric crosslinking agent, carboxyl-terminated poly(ethylene glycol) (PEG) of different molecular weights. Both the swelling and mechanical (tensile) properties of PGLD hydrogels crosslinked with PEG were measured and compared with the previous glutaric acid crosslinking system. The resultant PGLD films showed higher gel fraction and greater swelling capacity even at low PEG concentrations compared to those crosslinked with glutaric acid, probably due to the combined effect of the hydrophilicity and long chain effect of the PEG crosslinker. The values of the Young’s modulus and tensile strength were also higher for crosslinked films from PEG than from glutaric acid at a given (lower) crosslinker concentration. In addition, both the swelling and tensile properties of the PGLD hydrogels were largely affected by the crosslinker concentration.