STUDIES ON THE ENTEROPATHOGENIC, FACULTATIVELY HALOPHILIC BACTERIA, VIBRIO PARAHAEMOLYTICUS. I. MORPHOLOGICAL, CULTURAL AND BIOCHEMICAL PROPERTIES AND ITS TAXONOMICAL POSITION.
STUDIES ON THE ENTEROPATHOGENIC, FACULTATIVELY HALOPHILIC BACTERIA, VIBRIO PARAHAEMOLYTICUS. I. MORPHOLOGICAL, CULTURAL AND BIOCHEMICAL PROPERTIES AND ITS TAXONOMICAL POSITION.
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对肠病性兼性嗜盐细菌副溶血弧菌的研究。
DOI：
10.7883/yoken1952.21.313
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发表时间：
1968
期刊：
影响因子：
--
通讯作者：
Kazumichi Tamura
中科院分区：
文献类型：
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作者：
R. Sakazaki;S. Iwanami;Kazumichi Tamura
在日本，有吃生海鱼的习惯，一到夏季就接连发生与海鱼和鱼制品有关的急性肠胃炎症状的食物中毒事件。最近，一群兼性嗜盐生物作为食物中毒的病原体引起了日本研究者的极大兴趣。该生物最早是由Fujino和他的同事（1951年、1953年）报道的，他们在一次涉及272人（包括20人死亡）的肠胃炎爆发的尸检材料中发现了该生物，并在被认为是该爆发的致病食物的煮熟和半干的小沙丁鱼中发现了该生物。Takikawa（1958）研究了一种肠致病性兼性嗜盐菌的34株菌株，除1株外，其余菌株均在含有4%氯化钠的普通琼脂平板上从几次胃肠炎暴发患者的粪便中分离出来。33株菌株在含有0.5 M（2.9%）氯化钠的培养基上大量生长，具有相似的形态和生化特征。剩余菌株为上述Fujino等人的菌体。Takikawa认为Fujino et al.的生物可能与他的生物属于同一类群。此外，他还通过喂养使11名志愿者患上了胃肠炎。在Takikawa事件之后，许多日本调查人员开始关注这种生物，这种生物已经从与海鱼及其产品有关的肠胃炎的进一步爆发中反复分离出来。现在，据说在日本确诊的细菌性肠胃炎暴发中，有50%以上可能是由这种微生物引起的。宫本和他的同事（1960,1961a, 1961b）、Hone和他的同事（1963）以及Wagatsuma（1962）对这种生物进行了生态学研究。这些研究人员描述说，这种生物经常在沿海海水和海鱼中被发现，但在远洋中却没有。尽管有上述描述，许多重要问题仍然悬而未决。例如，生物的分类位置是未知的。虽然Fujino et al.和Takikawa分别为该生物提出了副溶血性巴斯德菌和肠炎假单胞菌的名称，但从其形态学和生化特性可以明显看出，它既不属于巴斯德菌，也不属于肠炎假单胞菌
In the summer season, food poisoning with symptoms of acute gastro-enteritis implicating in sea-fish and fish-products breaks out in succession in Japan, where it is a custom for the people to eat raw sea-fish. Recently, a group of facultatively halophilic organisms has attracted much interest of the Japanese investigators as a causative agent of the food poisoning. The organism in question was first reported by Fujino and his co-workers (1951, 1953) who had found the organism in autopsy materials collected from an outbreak of gastro-enteritis which involved 272 persons, including 20 fatal ones, and in•gshirasuboshi•h, or boiled and semi-dried young sardine, which was considered as the causative foodstuff of the outbreak. Takikawa (1958) studied 34 strains of an enteropathogenic, facultatively halophilic organism, all of which, except one, had been isolated on ordinary agar plate containing 4 % sodium chloride from the feces of patients in several outbreaks of gastro-enteritis. The 33 strains grew profusely in/on media containing 0.5 M (2.9 %) sodium chloride and possessed similar morphological and biochemical characteristics. The remaining strain was of the organism of Fujino et al. mentioned above. Takikawa concluded that the organism of Fujino et al. might belong to the same group as his organism. In addition, he was able to produce gastro-enteritis in 11 human volunteers by feeding. After Takikawa, many Japanese investigators paid attention to the organism, which has been isolated repeatedly from further outbreaks of gastro-enteritis implicating in sea-fish and its products. Now, it is said that over 50 % of the diagnosed outbreaks of bacterial gastro-enteritis in Japan may have been caused by the organism. The organism was studied ecologically by Miyamoto and his co-workers (1960, 1961a, 1961b), Hone and his co-workers (1963), and Wagatsuma (1962). These investigators described that the organism had been found frequently in coastal seawater and sea-fish but not in pelagic. In spite of the description mentioned above, many important questions are still in abeyance. For example, the taxonomical position of the organism is unknown. Although Fujino et al. and Takikawa proposed the names Pasteurella parahemolytica and Pseudomonas enteritis, respectively, for the organism, it is obvious from its morphological and biochemical properties that it belongs neither to Pasteurella nor to