Hair density, hair diameter and the prevalence of female pattern hair loss
Hair density, hair diameter and the prevalence of female pattern hair loss
复制标题
DOI：
10.1046/j.1365-2133.2001.04018.x
复制
发表时间：
2001-02-01
影响因子：
10.3
通讯作者：
Messenger, AG
中科院分区：
文献类型：
--
作者：
Birch, MP;Messenger, JF;Messenger, AG
背景女性脱发很常见，但对其患病率的估计差异很大。女性型脱发的临床诊断和头发密度和头发直径的客观测量之间的关系以前没有被evaluated.Objectives确定女性型脱发的患病率和相关的临床表现，头发密度和头发diameter.Methods我们检查了377名妇女，年龄18-99岁，患者因与毛发生长无关的主诉而就诊于普通皮肤科诊所（样本）。第二组47名患有典型女性脱发的女性被纳入头发密度、头发直径和临床诊断之间关系的分析中。头发密度测量使用摄影方法，在每个主题的长轴和短轴直径进行了测量，在随机抽样的50 hairs.Results 6%的妇女年龄在50岁以下齿轮被诊断为女性型脱发，增加到38%的主题年龄在70岁及以上，平均+/- SEM头发密度在35岁时为293 +/- 61.3根头发cm（-2），在70岁时下降到211 +/- 55.1根头发cm（-2）。头发密度在样本中呈正态分布。大多数被归类为女性型脱发的女性的头发密度在正态分布的下半部分。脱发的感觉主要由低头发密度决定（ANOVA P < 0.001），但是在被分类为Ludwig I脱发的女性和无脱发组之间的头发密度存在重叠，这部分地由平均头发直径的差异来解释（ANOVA P < 0.001）。低头发密度与所有直径的头发较少。结论女性的头发密度分布为正态变量，表明它是一个多因素的性状。女性型脱发的女性头发密度福尔斯低于平均值，但在正态分布的范围内，尽管其他因素，包括头发直径，可能会影响脱发的主观印象。头发直径数据表明，低头发密度不是由于毛囊大小的逐渐减少，毛囊小型化可能发生在单个头发周期的空间内。
Background Female pattern hair loss is common but Estimates of its prevalence have varied widely. The relationships between the clinical diagnosis of female pattern hair loss and objective measurements of hair density and hair diameter have not previously been evaluated.Objectives To determine the prevalence of female pattern hair loss and to relate the clinical findings to hair density and hair diameter.Methods We examined 377 women, aged 18-99 years, who presented to a general dermatology clinic with complaints unrelated to hair growth (the unselected sample). A second group of 47 women referred with typical female pattern hair loss was included in analyses of the relationships between hair density, hair diameter and the clinical diagnosis. Hair density was measured using a photographic method, In each subject the major and minor axis diameters were measured in a random sample of 50 hairs.Results Six per cent of women aged under 50 gears were diagnosed as having female pattern hair loss, increasing to 38% in subjects aged 70 years and over, The mean +/- SEM hair density was 293 +/- 61.3 hairs cm(-2) at age 35 years, falling to 211 +/- 55.1 hairs cm(-2) at age 70 years, Hair density showed a normal distribution in the unselected sample. Most women classified as having female pattern hair loss had hair densities within the lower half of the normal distribution. The perception of hair loss was determined mainly by low hair density (ANOVA P < 0.001), but there was overlap in hair density between women classified as having Ludwig I hair loss and the no hair loss group, which was partly accounted for by differences in mean hair diameter (ANOVA P < 0.001). Low hair density was associated with fewer hairs of all diameters.Conclusions Hair density in women is distributed as a normal variable, indicating that it is determined as a multifactorial trait. Women with female pattern hair loss have a hair density which falls below the mean but lies within the spectrum of the normal distribution, although other factors, including hair diameter, may affect the subjective impression of hair loss. The hair diameter data suggest that low hair density is not due to progressive diminution in hair follicle size and that follicular miniaturization may occur within the space of a single hair cycle.