Type 2 Diabetes and Mild Cognitive Impairment

Type 2 Diabetes and Mild Cognitive Impairment
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发表时间:
2012
影响因子:
0.3
通讯作者:
Qu Mei
Qu Mei
中科院分区:
生物学4区
文献类型:
--
作者:
Qu Mei

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阿尔采末病(Alzheimers 'disease,AD)是一个持续的病理生理过程,包括MCI前期(轻度认知障碍,MCI)、MCI和痴呆。对于AD的临床过程的不可逆性,早期发现并在MCI前或MCI期进行正确治疗,对延缓甚至逆转AD的进程具有重要意义。是MCI和AD的独立危险因素。本文简要回顾了T2DM与认知功能障碍可能相关机制的现有概念。
Alzheimers's disease(AD) is a continuous pathological physiology process,including pre-MCI(mild cognitive impairment,MCI),MCI and dementia.For the irreversible of the clinical course of AD,finding early and treat right in the stage of preMCI or MCI are very important for slowing down or even reverse the procession of AD.Research shows that type 2 diabetes mellitus(T2DM) is an independent risk factor for MCI and AD.This manuscript is a brief review of current concepts in the mechanisms potentially linking T2DM with cognitive impairment.