Glycoconjugates of gadolinium complexes for MRI applications
Glycoconjugates of gadolinium complexes for MRI applications
复制标题
DOI：
10.1039/b517997a
复制
发表时间：
2006-01-01
影响因子：
4.9
通讯作者：
Parker, D
中科院分区：
文献类型：
--
作者：
Fulton, DA;Elemento, EM;Parker, D
对含有12个葡萄糖或半乳糖基团通过四个树枝状楔形连接到中心Gd络合物的C-4对称的中等分子量共轭化合物的例子进行了表征；从有效的运动耦合和第二球形水分子的大贡献来解释它们增强的弛豫性能。
Examples of C-4 symmetric, medium MW conjugates incorporating 12 glucose or galactose groups linked via four dendritic wedges to a central Gd complex have been characterised; their enhanced relaxivity is interpreted in terms of effective motional coupling and large contributions from second sphere water molecules.