REDUCED-SIZE GRAFTS - THE SOLUTION FOR HEPATIC-ARTERY THROMBOSIS AFTER PEDIATRIC LIVER-TRANSPLANTATION

REDUCED-SIZE GRAFTS - THE SOLUTION FOR HEPATIC-ARTERY THROMBOSIS AFTER PEDIATRIC LIVER-TRANSPLANTATION
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DOI:
10.1016/0022-3468(95)90609-6
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发表时间:
1995-01-01
影响因子:
2.4
通讯作者:
BUSUTTIL, RW
BUSUTTIL, RW
中科院分区:
医学3区
文献类型:
--
作者:
JURIM, O;CSETE, M;BUSUTTIL, RW

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缩小尺寸肝移植(RSG)的开发是为了缓解儿科患者的供体短缺,特别是那些需要紧急移植的患者。理论上,与整个儿科移植物相比,RSG可用于吻合的肝动脉尺寸较大,不太可能导致肝动脉血栓形成(HAT)。因此,作者回顾了他们使用HAT的经验,比较了接受急诊肝移植的儿科患者的RSG和全肝移植。尽管受者的疾病严重程度(UNOS状态IV),以及在复位过程中对移植物的内在损伤,但在急诊儿科移植的RSG后未观察到HAT。相比之下,29%接受紧急移植的儿童受者有HAT。RSG是一种安全的替代全肝移植的儿科肝移植,并可能减少HAT的发生率。版权所有(C)1995由W.B.桑德斯公司
Reduced size liver grafts (RSG) were developed to alleviate the donor shortage for pediatric patients, particularly those requiring emergency transplantation. In theory, the large size of the hepatic artery available for anastomosis from RSG, as opposed to whole pediatric grafts, is less likely to lead to hepatic artery thrombosis (HAT). Therefore, the authors reviewed their experience with HAT, comparing RSG and whole-liver grafts in pediatric patients undergoing emergency liver transplantation. Despite the severity of illness of the recipients (UNOS status IV), and the intrinsic damage to the graft during reduction, HAT was not seen after RSG for emergency pediatric transplantation. in contrast, 29% of pediatric recipients who received whole grafts for emergency transplantation had HAT. RSG is a safe alternative to whole-liver grafts for pediatric liver transplantation, and may reduce the incidence of HAT. Copyright (C) 1995 by W.B. Saunders Company