Neuron production, neuron number, and structure size are seasonally stable in the hippocampus of the food-storing black-capped chickadee (Poecile atricapillus)
Neuron production, neuron number, and structure size are seasonally stable in the hippocampus of the food-storing black-capped chickadee (Poecile atricapillus)
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DOI：
10.1037/0735-7044.118.2.345
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发表时间：
2004-04-01
影响因子：
1.9
通讯作者：
Sherry, DF
中科院分区：
文献类型：
--
作者：
Hoshooley, JS;Sherry, DF
黑顶山雀 (Poecile atricapillus) 海马体的神经元募集在秋季的发生率高于一年中的其他时间。为了确定这种募集的增加是否是由于神经元产量增加所致，我们在 10 月至 3 月期间在野外捕获了山雀，并注射了细胞诞生标记物 5-溴-2'-脱氧尿苷。两周后，过量处死家禽，测定海马神经元产生、细胞凋亡、神经元数量和海马体积。十月、十一月、一月、二月和三月收集的山雀在神经元产生、细胞凋亡、海马体积或神经元数量方面没有差异。这些发现表明，秋季山雀海马体中神经元募集的增加并不是由于神经元产生的增加，而是由于新神经元的存活率提高。
Neuronal recruitment in the black-capped chickadee (Poecile atricapillus) hippocampus occurs at a higher rate in the fall than at other times of the year. As a means of determining whether this increase in recruitment results from greater neuron production, chickadees were caught in the wild between October and March and injected with the cell-birth marker 5-bromo-2'-deoxyuridine. Two weeks later, birds were killed by overdose, and hippocampal neuron production, apoptosis, neuron number, and hippocampal volume were determined. Chickadees collected in October, November, January, February, and March did not differ in neuron production, apoptosis, hippocampal volume, or neuron number. These findings indicate that increases in neuronal recruitment in the chickadee hippocampus in the fall do not result from increased neuron production, but instead, enhanced survival of new neurons.