Clinical Features of Ocular Ischemic Syndrome and Risk Factors for Neovascular Glaucoma.
Clinical Features of Ocular Ischemic Syndrome and Risk Factors for Neovascular Glaucoma.
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DOI：
10.3341/kjo.2016.0067
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发表时间：
2017-08-01
影响因子：
--
通讯作者：
Park, Sang Woo
中科院分区：
文献类型：
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作者：
Kim, Yung Hui;Sung, Mi Sun;Park, Sang Woo
目得：目的：探讨眼缺血综合征的临床特点及预后，探讨新生血管性青光眼（NVG）发生的危险因素。我们记录了症状发作和诊断之间的时间长度、视力、眼压、眼前节和眼后节的临床表现、荧光素血管造影、全身疾病、吸烟史和任何同侧颈动脉狭窄的程度。结果：本组病例平均年龄67.9 ± 12.5岁，男21例，女4例。初次检查时，最小分辨率角（logMAR）的平均对数为2.02 ± 1.26，平均眼压为21.0 ± 10.3 mmHg。25例（25只眼）中17只眼发生NVG，平均病程12.6 ± 14.0个月。症状发作和诊断之间的时间长度（p = 0.025）和同侧颈动脉狭窄的程度（p = 0.032）被确定为NVG的重要危险因素。在最后一次随访时，平均logMAR视力为3.13 ± 1.24，无论是否发生NVG，预后均较差。结论：总体而言，眼缺血综合征的预后非常差。NVG的风险随着症状发作和诊断之间的时间长度以及同侧颈动脉狭窄的严重程度而增加。
PURPOSE: We aimed to examine the clinical features and prognosis of ocular ischemic syndrome and to investigate the risk factors for the development of neovascular glaucoma (NVG).METHODS: The medical records from 25 patients (25 eyes) who were diagnosed with ocular ischemic syndrome were retrospectively analyzed. We recorded the length of time between symptom onset and diagnosis, visual acuity, intraocular pressure, clinical findings of the anterior and posterior segments of the eye, fluorescein angiography, systemic diseases, smoking history, and the extent of any ipsilateral carotid artery stenosis. The risk factors for NVG in patients with ocular ischemic syndrome were investigated.RESULTS: The mean age was 67.9 ± 12.5 years, and 21 men and 4 women were included in this study. At initial examination, the mean logarithm of the minimum angle of resolution (logMAR) was 2.02 ± 1.26, and the mean intraocular pressure was 21.0 ± 10.3 mmHg. Among 25 eyes of the 25 patients, NVG occurred in 17 eyes after a mean period of 12.6 ± 14.0 months. The length of time between symptom onset and diagnosis (p = 0.025) and the extent of ipsilateral carotid artery stenosis (p = 0.032) were identified as significant risk factors for NVG. At the final follow-up, the mean logMAR visual acuity was 3.13 ± 1.24, showing a poor prognosis regardless of whether NVG occurred.CONCLUSIONS: Overall, the prognosis for ocular ischemic syndrome is very poor. The risk of NVG increases with the length of time between symptom onset and diagnosis, as well as with the severity of ipsilateral carotid artery stenosis.