Smartphone-based Anterior Segment Imaging: A Comparative Diagnostic Accuracy Study of a Potential Tool for Blindness Prevalence Surveys.

Smartphone-based Anterior Segment Imaging: A Comparative Diagnostic Accuracy Study of a Potential Tool for Blindness Prevalence Surveys.
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基于智能手机的眼前段成像:失明患病率调查潜在工具的比较诊断准确性研究。

DOI:
10.1080/09286586.2021.1980589
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发表时间:
2022-10
影响因子:
1.8
通讯作者:
Keenan JD
Keenan JD
中科院分区:
医学4区
文献类型:
--
作者:
Kumar A;Ali FS;Stevens VM;Melo JS;Venkatesh Prajna N;Lalitha P;Srinivasan M;Bhandari G;Bhandari S;Maamari RN;Fletcher DA;Lietman TM;Keenan JD

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通过提供准确的角膜混浊诊断,确定智能手机摄影是否可以作为失明患病率调查的有用辅助工具。在印度南部的一家眼科医院,174名在过去5年中接受了角膜培养的感染性角膜炎患者参加了一项诊断准确性研究。两只眼睛都接受了眼科医生进行的裂隙灯检查,然后用手持数字单反(SLR)相机和连接到外部附件的智能手机相机进行眼前段摄影,外部附件提供放大和照明。根据裂隙灯检查评估摄影诊断的准确性。174名受试者中,培养眼有90只眼角膜混浊,对侧眼无混浊,无穿透性角膜移植或遗失照片。相对于裂隙灯检查,使用智能手机的默认设置诊断角膜混浊的敏感性为68%(95%CI 58~77%),使用SLR诊断角膜混浊的敏感性为59%(95%CI 49~69%),特异性为97%(95%CI 93~100%),SLR的特异性为97%(95%CI 92~100%)。基于智能手机的角膜混浊诊断对较大的疤痕(直径2 mm或更大的混浊占81%)、视觉上较明显的疤痕(视力低于20/400的眼睛占100%)和较新的瘢痕(过去12个月培养的眼睛占85%)的敏感性更高。智能手机与外部附件连接的诊断性能虽然有些不同,但对除最小不透明外的所有部位都表现出高特异度和高敏感性。
to determine if smartphone photography could be a useful adjunct to blindness prevalence surveys by providing an accurate diagnosis of corneal opacity. 174 patients with infectious keratitis who had undergone corneal culturing over the past 5 years were enrolled in a diagnostic accuracy study at an eye hospital in South India. Both eyes had an ophthalmologist-performed slit lamp examination, followed by anterior segment photography with a handheld digital single lens reflex (SLR) camera and a smartphone camera coupled to an external attachment that provided magnification and illumination. The diagnostic accuracy of photography was assessed relative to slit lamp examination. 90 of 174 enrolled participants had a corneal opacity in the cultured eye and no opacity in the contralateral eye, and did not have a penetrating keratoplasty or missing photographs. Relative to slit lamp examination, the sensitivity of corneal opacity diagnosis was 68% (95%CI 58–77%) using the smartphone’s default settings and 59% (95%CI 49–69%) using the SLR, and the specificity was 97% (95%CI 93–100%) for the smartphone and 97% (95%CI 92–100%) for the SLR. The sensitivity of smartphone-based corneal opacity diagnosis was higher for larger scars (81% for opacities 2mm in diameter or larger), more visually significant scars (100% for eyes with visual acuity worse than 20/400), and more recent scars (85% for eyes cultured in the past 12 months). The diagnostic performance of a smartphone coupled to an external attachment, while somewhat variable, demonstrated high specificity and high sensitivity for all but the smallest opacities.
DOI: 10.4103/0301-4738.181742
发表时间: 2016-03-01
影响因子: 3.1
作者:
Ludwig, Cassie A.;Murthy, Somasheila I.;Chang, Robert T.
通讯作者: Chang, Robert T.
DOI: 10.2147/opth.s134656
发表时间: 2017
期刊: Clinical ophthalmology (Auckland, N.Z.)
影响因子: --
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发表时间: 2017-10-01
期刊: CORNEA
影响因子: 2.8
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发表时间: 2014-09-01
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