Multiparametric corticofugal modulation and plasticity in the auditory system

Multiparametric corticofugal modulation and plasticity in the auditory system
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DOI:
10.1038/nrn1222
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发表时间:
2003-10
影响因子:
34.7
通讯作者:
N. Suga;Xiaofeng Ma
N. Suga;Xiaofeng Ma
中科院分区:
医学1区
文献类型:
--
作者:
N. Suga;Xiaofeng Ma

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成年动物的听觉系统可以通过听觉经验进行重组。听觉皮层、皮质系统和胆碱能基底前脑对这种重组至关重要。听觉系统可以经历两种不同形式的重组——扩张和压缩。尽管在不同物种和不同的感觉系统中都发现了扩展重组,但压缩重组只在八字蝠的听觉系统中发现,这是高度专业化的回声定位。在这里,我们回顾了最近的进展,我们的理解皮质系统和听觉系统的重组。
The auditory systems of adult animals can be reorganized by auditory experience. The auditory cortex, the corticofugal system and the cholinergic basal forebrain are crucial for this reorganization. The auditory system can undergo two different forms of reorganization — expansion and compression. Whereas expanded reorganization has been found in different species and different sensory systems, compressed reorganization has only been found in the auditory system of the moustached bat, which is highly specialized for echolocation. Here, we review recent progress in our understanding of the corticofugal system and the reorganization of the auditory system.