Factors Associated With Prevalent HIV Infection Among Kenyan MSM: The Anza Mapema Study
Factors Associated With Prevalent HIV Infection Among Kenyan MSM: The Anza Mapema Study
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DOI：
10.1097/qai.0000000000001512
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发表时间：
2017-11-01
影响因子：
3.6
通讯作者：
Otieno, Fredrick O.
中科院分区：
文献类型：
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作者：
Kunzweiler, Colin P.;Bailey, Robert C.;Otieno, Fredrick O.
背景：为了为男男性行为者 (MSM) 未来的 HIV 治疗和护理计划提供信息，我们评估了参加前瞻性 Anza Mapema 队列研究的 MSM 中先前诊断出的 HIV 阳性且失护理 (PDOC) 或新诊断的 HIV 阳性且失护理 (NDOC) HIV 感染的患病率和相关因素。方法：参与者年龄为 18 岁及以上，报告在过去 6 个月内与男性发生口交或肛交，并且尚未接受 HIV 护理或治疗过去 3 个月内接受过抗逆转录病毒治疗。入组时，男性接受了艾滋病毒感染检测，并通过音频计算机辅助自我访谈完成了调查问卷。使用多项 Logistic 回归来确定 PDOC 或 NDOC HIV 感染与 HIV 阴性状态之间的关联。结果：在 711 名登记男性中，75 名 (10.5%) 血清呈阳性，其中包括 21 名 PDOC 和 54 名 NDOC 男性。在多变量模型中，在童年时期经历过令人不安的性经历、最近经历过 MSM 创伤且没有报告有害饮酒的男性中，PDOC 状态比 HIV 阴性状态更有可能。 NDOC 感染状况在 30 岁及以上且已完成治疗的男性中更为常见
Background: To inform future HIV treatment and care programs for men who have sex with men (MSM), we assessed the prevalence of and factors associated with previously diagnosed HIV-positive and out-of-care (PDOC) or newly diagnosed HIV-positive and out-of-care (NDOC) HIV infection among MSM enrolled in the prospective Anza Mapema cohort study.Methods: Participants were aged 18 years and older, reported oral or anal sex with a man in the past 6 months and were not already in HIV care or taking antiretroviral therapy in the past 3 months. At enrollment, men were tested for HIV infection and completed questionnaires through audio computer-assisted self-interview. Multinomial logistic regression was used to identify associations with PDOC or NDOC HIV infection, relative to HIV-negative status.Results: Among 711 enrolled men, 75 (10.5%) were seropositive including 21 PDOC and 54 NDOC men. In multivariable modeling, PDOC status was more likely than HIV-negative status among men who had experienced upsetting sexual experiences during childhood, had recently experienced MSM trauma, and did not report harmful alcohol use. NDOC infection status was more common among men aged 30 years and older and who had completed