Pneumatosis intestinalis associated with fatal childhood dermatomyositis.
Pneumatosis intestinalis associated with fatal childhood dermatomyositis.
复制标题
肠积气症与致命的儿童皮肌炎有关。
DOI：
10.1542/peds.61.1.127
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发表时间：
1978
期刊：
影响因子：
8
通讯作者：
E. Stiehm
中科院分区：
文献类型：
--
作者：
Thomas J. Fischer;Louis Cipel;E. Stiehm
胃肠道并发症是常见的儿童皮肌炎。1肺气肿只有两次报告，这两个孩子都有一个良性的过程。2，3我们现在报告一个男孩的外观肺气肿之前，结肠穿孔，腹膜炎和死亡。
病例报告
一名8岁半的男孩出现一个月的肌肉疼痛、无力、吞咽困难和眶周肿胀病史。皮肌炎的诊断是通过肌酶水平升高、肌电图异常和肌肉活检标本确定的。尽管接受泼尼松治疗（60 mg/天），但仍发生呼吸障碍，并静脉注射甲氨蝶呤（1 mg/kg/周），导致临床改善。在接下来的9个月里，患者因呼吸无力住院两次，第三次因腹痛住院，第三次因腹痛住院，为此他接受了剖腹手术，并附带阑尾切除术。
Gastrointestinal complications are frequent in childhood dermatomyositis.1 Pneumatosis intestinalis has been reported only twice and both children had a benign course.2,3 We now report a boy in whom the appearance of pneumatosis intestinalis preceded colonic perforation, peritonitis, and death.
CASE REPORT
A boy 8½ years of age presented with a one-month history of muscle pain, weakness, dysphagia, and periorbital swelling. A diagnosis of dermatomyositis was established by elevated muscle enzyme levels and an abnormal electromyogram and muscle biopsy specimen. Despite prednisone therapy (60 mg/day), respiratory impairment developed and intravenous methotrexate (1 mg/kg/wk) was added, resulting in clinical improvement. During the next nine months the patient was hospitalized twice for respiratory weakness and a third time for abdominal pain, for which he underwent a third time for abdominal pain, for which he underwent a laparotomy with an incidental appendectomy.