Using Azobenzene-Embedded Self-Assembled Monolayers To Photochemically Control Cell Adhesion Reversibly
Using Azobenzene-Embedded Self-Assembled Monolayers To Photochemically Control Cell Adhesion Reversibly
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使用偶氮苯嵌入的自组装单层光化学可逆地控制细胞粘附
DOI：
10.1002/anie.200901130
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发表时间：
2009-01-01
影响因子：
16.6
通讯作者：
Jiang, Xingyu
中科院分区：
文献类型：
--
作者：
Liu, Dingbin;Xie, Yunyan;Jiang, Xingyu
细胞点：由两种类型的烷硫醇组成的混合自组装单分子膜--一种含有以肽终止的偶氮苯单元，另一种含有抵抗非特异性细胞黏附的六(乙二醇基)基团--使细胞黏附能够被光化学调节。偶氮苯部分在E和Z构型之间的可逆转化允许表面支持或抵抗细胞黏附。
A celling point: A mixed self‐assembled monolayer comprising two types of alkanethiols—one containing an azobenzene unit terminated with a peptide, the other containing a hexa(ethylene glycol) group that resists nonspecific cell adhesion—enables cell adhesion to be modulated photochemically. The reversible conversion of the azobenzene moiety betweenEandZconfigurations allows the surface to either support or resist cell adhesion.