Pectus excavatum in children with laryngomalacia
Pectus excavatum in children with laryngomalacia
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DOI：
10.1016/j.ijporl.2013.07.033
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发表时间：
2013-10-01
影响因子：
1.5
通讯作者：
Bent, John
中科院分区：
文献类型：
--
作者：
Schaerer, Daniel;Virbalas, Jordan;Bent, John
背景：喉软化症是最常见的先天性喉异常，与多种疾病有关，包括胃反流、睡眠呼吸暂停、肌张力低下和发育迟缓。漏斗胸 (PE) 是最常见的胸壁畸形，影响 1-300/1000 人。虽然许多作者推测 PE 与喉软化症之间存在关系，但没有已发表的数据来证实这种关联。目标：检验转诊到我们儿科耳鼻喉科诊所评估喉软化症的患者比一般人群表现出更高的 PE 发生率的假设。方法：对前瞻性入组的因喉软化症（2008 年 1 月至 2012 年 6 月）到三级护理机构、医院就诊的儿童进行回顾性审查基于小儿耳鼻喉科实践。检查每张图表是否同时诊断胸肌畸形。结果：在 137 名喉软化症患者中，9 名 (6.6%) 有 PE 记录。这表明与没有喉软化症的儿童相比，PE 发生率显着增加 (p = 0.001)。 9 名 PE 儿童中有 4 名因喉软化症接受了声门上成形术，这一比例明显高于接受声门上成形术的孤立性喉软化症儿童的 9/128 (p = 0.004)。 结论：这项研究表明喉软化症与 PE 之间存在关联。儿科耳鼻喉科医生应该认识到这种关系，尽管需要进一步的研究来阐明这种关联的性质。 (C) 2013 Elsevier Ireland Ltd. 保留所有权利。
Background: Laryngomalacia is the most common congenital laryngeal anomaly and is associated with several disorders including gastric reflux, sleep apnea, hypotonia and failure to thrive. Pectus excavatum (PE) is the most common chest wall deformity affecting 1-300/1000 individuals. Though many authors presume a relationship between PE and laryngcimalacia, there is no published data to establish this association.Goal: To test the hypothesis that patients referred to our pediatric otolaryngology clinic for evaluation of laryngomalacia exhibit higher rates of PE than the general population.Methods: Retrospective review of prospectively enrolled children who presented with laryngomalacia (January 2008-June 2012) to a tertiary care, hospital based, pediatric otolaryngology practice. Each chart was examined for a concurrent diagnosis of pectus deformity.Results: Of the 137 laryngomalacia patients, 9 (6.6%) had documented PE. This represents a significantly increased rate of PE when compared to children without laryngomalacia (p = 0.001). Four of the 9 children with PE underwent supraglottoplasty for laryngomalacia, a significantly greater proportion than the 9/128 of the children with isolated laryngomalacia who underwent supraglottoplasty (p = 0.004).Conclusions: This study suggests an association between laungomalacia and PE. Pediatric otolaryngolgists should be cognizant of this relationship, though further studies are needed to elucidate the nature of this association. (C) 2013 Elsevier Ireland Ltd. All rights reserved.