Ultrasound biomicroscopy of the aging rhesus monkey ciliary region
Ultrasound biomicroscopy of the aging rhesus monkey ciliary region
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DOI：
10.1097/00006324-200106000-00014
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发表时间：
2001-06-01
影响因子：
1.4
通讯作者：
Kaufman, PL
中科院分区：
文献类型：
--
作者：
Glasser, A;Croft, MA;Kaufman, PL
对活体恒河猴眼睫状体区域进行超声生物显微镜检查，以确定可能与老花眼进展相关的年龄依赖性变化。将猴子麻醉并进行药物睫状肌闭合术，用眼睑窥镜将眼睑保持打开，并将缝合线放置在内直肌和外直肌下方。对眼睛的鼻和颞象限进行超声生物显微镜成像，并将实时图像记录到录像带中。进行随后的图像分析以获得睫状体区域的客观形态测量。测量睫状体内曲率半径、外曲率半径、内弧长度、面积、厚度、周长、小带纤维长度和周围空间。计算了小带空间。颞象限的周围空间随着年龄的增加而减小。其他形态学测量与年龄或体重没有显着相关。与颞象限和鼻象限相比，大多数形态学测量结果显着不同。经常观察到后小带纤维的分叉。尽管颞部晶状体周围空间是唯一随年龄变化的测量值，但活体恒河猴睫状体区域的超声生物显微镜确实发现了明显的鼻部与颞部不对称性，这可能反映了与会聚相关的调节的解剖学要求。
Ultrasound biomicroscopy of the living rhesus monkey ocular ciliary region was undertaken to identify age-dependent changes that might relate to the progression of presbyopia. Monkeys were anesthetized and pharmacologically cyclopleged, the eyelids were held open with a lid speculum, and sutures were placed beneath the medial and lateral rectus muscles. Ultrasound biomicroscopy imaging of the nasal and temporal quadrants of the eye were performed, and the live images were recorded to videotape. Subsequent image analysis was performed to obtain objective morphometric measurements of the ciliary body region. The ciliary body inner radius of curvature, outer radius of curvature, inner are length, area, thickness, perimeter, zonular fiber length, and circumlental space were measured. Zonular space was calculated. The circumlental space decreased with increasing age in the temporal quadrant. The other morphologic measurements were not significantly correlated with age or body weight. Most morphologic measurements were significantly different comparing temporal vs. nasal quadrants. Bifurcation of the posterior zonular fibers was frequently observed. Although temporal circumlental space was the only measurement found to change with age, ultrasound biomicroscopy of the living rhesus ciliary region did identify distinct nasal vs. temporal asymmetries, which may reflect anatomical requirements for convergence-associated accommodation.