Pulp response to dentine adhesives: A study on mature human pulps.
Pulp response to dentine adhesives: A study on mature human pulps.
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DOI：
10.4103/1305-7456.119060
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发表时间：
2013-09
影响因子：
--
通讯作者：
Tziafas D
中科院分区：
文献类型：
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作者：
Kouros P;Koliniotou-Koumpia E;Koulaouzidou E;Helvatjoglu-Antoniades M;Tziafas D
临床研究含 12-甲基丙烯酰氧基十二烷基溴化吡啶鎓 (MDPB) 的市售自酸蚀粘合剂系统与其各自不含 MDPB 的粘合剂相比的抗菌效果，并评估用于人类牙齿时的牙髓反应。使用了六十二颗计划拔除的活人牙齿。根据制造商的建议，在牙齿颊面制备 V 类蛀牙，并用测试材料（Protect Bond/Clearfil AP-X、SE Bond/Clearfil AP-X 和 Dycal/Ketac Fill Plus）填充作为对照组。随机分为两组，牙齿保留在口内4周和8周。拔牙后，使用迈耶苏木精和曙红对牙齿进行脱钙、切片和染色，并改进布朗-布伦技术。在显微镜下对牙髓反应进行显微评估，并在立体显微镜下测量剩余牙本质厚度。对于测试的材料或术后评估期间，没有发现牙髓炎症或细菌浸润方面存在统计学上的显着差异。结果表明，在短期评估中，无论使用何种修复材料，都不存在数量差异。
To clinically investigate the antibacterial effects of a commercially available self-etch 12-methacryloyloxy- dodecylpyridinium bromide (MDPB)-containing adhesive system in comparison with its respective non-MDPB-containing adhesive and to evaluate the pulp responses when in use on human teeth. Sixty-two viable human teeth scheduled for extraction were used. Class V cavities were prepared on the buccal surfaces of the teeth and filled with the tested materials (Protect Bond/Clearfil AP-X, SE Bond/Clearfil AP-X and Dycal/Ketac Fill Plus) as a control group, according to manufacturer's recommendations. Randomly divided to two groups teeth remained intra-orally for 4 and 8 weeks. After extraction, teeth were decalcified, sectioned and stained using the Mayer's hematoxylin and eosin, and modified Brown-Brenn's technique. Pulp responses were evaluated microscopically under a microscope and remaining dentine thickness measured under a stereomicroscope. No statistically significant differences regarding pulp inflammation or bacterial infiltration were found either for the materials tested or for periods of post-operative evaluation. The results suggested that for a short period of evaluation there are no quantitative differences, regardless to restoring material used.