Cluster randomized trial of text message reminders to retail staff in tanzanian drug shops dispensing artemether-lumefantrine: effect on dispenser knowledge and patient adherence.
Cluster randomized trial of text message reminders to retail staff in tanzanian drug shops dispensing artemether-lumefantrine: effect on dispenser knowledge and patient adherence.
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DOI：
10.4269/ajtmh.14-0126
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发表时间：
2014-10
期刊：
影响因子：
--
通讯作者：
Schellenberg D
中科院分区：
文献类型：
--
作者：
Bruxvoort K;Festo C;Kalolella A;Cairns M;Lyaruu P;Kenani M;Kachur SP;Goodman C;Schellenberg D
青蒿素综合疗法在私人商店有售，但配药员的不良建议可能会影响患者的依从性。在坦桑尼亚的药店进行的这项随机分组试验中，82家选定的商店中有42家被随机分配接受短信提醒，提醒在分发蒿甲醚-苯芴醇（AL）时提供什么建议。在两组商店购买AL的合格患者在家中进行随访，并询问每次服用的剂量。配药员进行了采访，了解AL配药的做法和收到疟疾相关的短信。我们采访了来自77家商店的904名患者和110名配药员。尽管分配器知识有所改善，但两组间完成所有剂量（干预组68.3%，对照组69.8%，p [调整后] = 0.6）或在正确时间完成每次剂量（干预组33.1%，对照组32.6%，p [调整后] = 0.9）的依从性无差异。需要进一步研究短信在提高依从性方面的潜力。
Artemisinin combination therapies are available in private outlets, but patient adherence might be compromised by poor advice from dispensers. In this cluster randomized trial in drug shops in Tanzania, 42 of 82 selected shops were randomized to receive text message reminders about what advice to provide when dispensing artemether-lumefantrine (AL). Eligible patients purchasing AL at shops in both arms were followed up at home and questioned about each dose taken. Dispensers were interviewed regarding knowledge of AL dispensing practices and receipt of the malaria-related text messages. We interviewed 904 patients and 110 dispensers from 77 shops. Although there was some improvement in dispenser knowledge, there was no difference between arms in adherence measured as completion of all doses (intervention 68.3%, control 69.8%, p [adjusted] = 0.6), or as completion of each dose at the correct time (intervention 33.1%, control 32.6%, p [adjusted] = 0.9). Further studies on the potential of text messages to improve adherence are needed.
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影响因子：
7.4
作者：
Källander K;Tibenderana JK;Akpogheneta OJ;Strachan DL;Hill Z;ten Asbroek AH;Conteh L;Kirkwood BR;Meek SR
通讯作者：
Meek SR
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影响因子：
3.7
作者：
Briggs MA;Kalolella A;Bruxvoort K;Wiegand R;Lopez G;Festo C;Lyaruu P;Kenani M;Abdulla S;Goodman C;Kachur SP
通讯作者：
Kachur SP
影响因子：
168.9
作者：
Lester, Richard T.;Ritvo, Paul;Plummer, Francis A.
通讯作者：
Plummer, Francis A.
影响因子：
11.8
作者：
Mace, Kimberly E.;Mwandama, Dyson;Skarbinski, Jacek
通讯作者：
Skarbinski, Jacek
影响因子：
3
作者：
Kabanywanyi, Abdunoor M.;Lengeler, Christian;Genton, Blaise
通讯作者：
Genton, Blaise