Intent to receive HPV vaccine and reasons for not vaccinating among unvaccinated adolescent and young women: Findings from the 2006-2008 National Survey of Family Growth
Intent to receive HPV vaccine and reasons for not vaccinating among unvaccinated adolescent and young women: Findings from the 2006-2008 National Survey of Family Growth
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DOI：
10.1016/j.vaccine.2012.02.007
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发表时间：
2012-03-30
期刊：
影响因子：
5.5
通讯作者：
Leichliter, Jami S.
中科院分区：
文献类型：
--
作者：
Liddon, Nicole C.;Hood, Julia E.;Leichliter, Jami S.
背景和目的：在美国，女性HPV疫苗的覆盖率有所增加，尽管在实现高覆盖率方面仍然存在挑战。HPV疫苗的覆盖率仍然落后于其他常规推荐的青少年疫苗，这些覆盖率差距正在扩大。告知策略，以提高摄取，我们探讨相关的疫苗意向和描述的原因拒绝接种HPV疫苗的女性在一个全国代表性的样本中的青少年和年轻人在HPV疫苗availability.Methods的早期阶段：在2007- 2008年，1243名女性年龄在15-24岁，被问及HPV疫苗接种在全国家庭成长调查（NSFG）。对于未接种疫苗的妇女（n=955），我们评估了人口统计学和性行为相关的可能性，在未来12个月内接受疫苗的双变量和多变量分析的年龄。结果：少数（42.5%）未接种疫苗的受访者表示，他们打算在未来12个月内接受HPV疫苗：37.6%的青少年（15-19岁）和42.0%的年轻人（20-24岁）。有性经历的女性打算接种HPV疫苗的可能性是无性经历女性的两倍多（15-19岁：aOR = 2.39，95% CI = 1.15，4.94; 20-24岁：aOR = 2.17，95% CI = 1.08，4.33）。拥有健康保险与青少年可能接受HPV疫苗有关。西班牙裔年轻人比非西班牙裔白人更有可能接受HPV疫苗。没有HPV风险的信念和制度障碍是之前接种疫苗的两个最常见的原因。在不打算接种疫苗的未接种疫苗的妇女中，与有性经验的妇女相比，从未发生过性行为的受访者更有可能报告没有风险是不需要疫苗的主要原因（44.5 vs. 24.4%），但这一发现在我们有限的样本中仅具有轻微的显著性。在HPV疫苗获得许可后的第一年，大多数未接种疫苗的妇女表示她们不太可能寻求接种疫苗。接受HPV疫苗的意图与性经验有关，大多数不打算接种疫苗且从未发生过性行为的女性认为自己没有HPV风险或不需要HPV疫苗。这些发现强调了需要更好地传达有关HPV终身风险的信息，以及在性行为开始前接受HPV疫苗的重要性。这些发现应该为增加疫苗的策略提供信息。
Background and purpose: HPV vaccine coverage for females has increased in the U.S., although challenges to achieving high coverage remain. HPV vaccine coverage continues to lag behind that of other routinely recommended adolescent vaccines and these gaps in coverage are widening. To inform strategies to improve uptake, we explore correlates of vaccine intention and describe reasons for refusing HPV vaccination among unvaccinated females in a nationally representative sample of adolescents and young adults during early stages of HPV vaccine availability.Methods: In 2007-2008,1243 females aged 15-24 years were asked about HPV vaccination in the National Survey of Family Growth (NSFG). For unvaccinated women (n=955), we evaluated demographic and sexual behavior correlates of likelihood to receive the vaccine in the next 12 months in bivariate and multivariable analyses by age. Correlates to the main reasons for foregoing vaccination are described.Results: A minority (42.5%) of unvaccinated respondents said they intended to receive HPV vaccine in the next 12 months: 37.6% of adolescents (15-19 years) and 42.0% of young adults (20-24 years). Sexually experienced women were more than twice as likely as non-sexually experienced women to intend to receive HPV vaccine (15-19 years: aOR = 2.39, 95% Cl = 1.15, 4.94; 20-24 years: aOR = 2.17, 95% Cl = 1.08, 4.33). Having health insurance was associated with being likely to receive HPV vaccine among adolescents. Hispanic young adults were more likely than non-Hispanic Whites to be likely to receive HPV vaccine. The belief of not being at risk for HPV and institutional barriers were the two most commonly cited reasons for foregoing vaccination. Among unvaccinated women who did not intend to get vaccinated, respondents who never had sex were more likely to report not being at risk as the main reason for not needing the vaccine compared to women with sexual experience (44.5 vs. 24.4%) but this finding was only marginally significant in our limited sample.Conclusion: In the first years immediately post-licensure of an HPV vaccine, the majority of unvaccinated women indicated that they were unlikely to seek vaccination. Intent to receive the HPV vaccine is tied to sexual experience and most women who do not intend to get vaccinated and have never had sex believe they are not at risk of HPV or do not need an HPV vaccine. These findings highlight the need to better communicate information regarding lifetime risk for HPV and the importance of receiving HPV vaccine prior to sexual initiation. These findings should inform strategies to increase vaccine Published by Elsevier Ltd.