KDOQI CLINICAL PRACTICE GUIDELINE FOR HEMODIALYSIS ADEQUACY: 2015 UPDATE
KDOQI CLINICAL PRACTICE GUIDELINE FOR HEMODIALYSIS ADEQUACY: 2015 UPDATE
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DOI：
10.1053/j.ajkd.2015.07.015
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发表时间：
2015-11-01
影响因子：
13.2
通讯作者：
Weiner, Daniel E.
中科院分区：
文献类型：
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作者：
Daugirdas, John T.;Depner, Thomas A.;Weiner, Daniel E.
自 1997 年以来，国家肾脏基金会的肾脏疾病结果质量计划 (KDOQI) 为慢性肾脏病 (CKD) 的各个阶段及相关并发症提供了循证指南。2015 年更新的 KDOQI 血液透析充分性临床实践指南旨在帮助护理患者准备血液透析和血液透析期间的从业人员。本次更新回顾的文献包括 2000 年至 2014 年 3 月期间发表的临床试验和观察性研究。新主题包括高频血液透析和风险；处方在起始时间、频率、持续时间和超滤率方面的灵活性；并且更加强调容量和血压的控制。证据质量和建议强度的评估遵循建议评估、制定和评价分级 (GRADE) 方法。讨论了证据的局限性，并为未来的研究提供了具体建议。
The National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQI) has provided evidence-based guidelines for all stages of chronic kidney disease (CKD) and related complications since 1997. The 2015 update of the KDOQI Clinical Practice Guideline for Hemodialysis Adequacy is intended to assist practitioners caring for patients in preparation for and during hemodialysis. The literature reviewed for this update includes clinical trials and observational studies published between 2000 and March 2014. New topics include high-frequency hemodialysis and risks; prescription flexibility in initiation timing, frequency, duration, and ultrafiltration rate; and more emphasis on volume and blood pressure control. Appraisal of the quality of the evidence and the strength of recommendations followed the Grading of Recommendation Assessment, Development, and Evaluation (GRADE) approach. Limitations of the evidence are discussed and specific suggestions are provided for future research.