Tea Consumption and Risk of Type 2 Diabetes: A Meta-Analysis of Cohort Studies
Tea Consumption and Risk of Type 2 Diabetes: A Meta-Analysis of Cohort Studies
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DOI：
10.1007/s11606-009-0929-5
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发表时间：
2009-05-01
影响因子：
5.7
通讯作者：
Zhu, Dalong
中科院分区：
文献类型：
--
作者：
Jing, Yali;Han, Guanjun;Zhu, Dalong
人们对饮茶与各种疾病的关系进行了广泛的研究，有几项流行病学研究调查了饮茶与2型糖尿病的关系；然而，这些研究的结果并不完全一致。对评估饮茶与2型糖尿病风险之间关系的研究进行荟萃分析。2008年11月，我们在PUBMED、MEDLINE、EMBASE和Cochrane系统评价数据库中进行了系统的文献检索。搜索仅限于英语研究。如果是1型糖尿病，动物研究被排除在外。两位作者确定了9项队列研究，并使用随机效应模型计算了总相对风险（rr）。我们确定了9项队列研究，包括324141名参与者和11400例2型糖尿病病例，随访时间为5至18年。经综合校正的相对危险度（RR）没有显示喝茶与降低2型糖尿病风险相关（RR, 0.96； 95%可信区间（CI）， 0.92-1.01）。我们的分层分析结果的证据显示，每天饮茶每千日元4杯（RR, 0.8; 95% CI, 0.7-0.93）可能在预防2型糖尿病中发挥作用。然而，性别和随访时间与2型糖尿病之间没有统计学上的显著关联。这项荟萃分析表明，每天每千日元一杯的饮茶量可能会降低患2型糖尿病的风险。
Tea consumption has been extensively studied in relation to various diseases, several epidemiologic studies have been performed to investigate the association of tea consumption with type 2 diabetes; however, the results of these studies were not entirely consistent.To conduct a meta-analysis of studies that assessed the association of tea consumption and the risk of type 2 diabetes.We performed a systematic literature search through November 2008 in PUBMED, MEDLINE, EMBASE, and Cochrane Database of Systematic Reviews. The search was limited to English-language studies. Studies were excluded if they were type 1 diabetes, animal studies. Nine cohort studies were identified by two authors, and summary relative risks (RRs) were calculated using a random-effects model.We identified nine cohort studies, including 324,141 participants and 11,400 incident cases of type 2 diabetes with follow-up ranging from 5 to 18 years. The summary adjusted RR did not show that tea consumption was associated with a reduced type 2 diabetes risk (RR, 0.96; 95% confidence interval (CI), 0.92-1.01). Evidence from the results of our stratified analyses revealed that tea consumption a parts per thousand yen4 cups per day (RR, 0.8; 95% CI, 0.7-0.93) might play a role in the prevention of type 2 diabetes. However, no statistically significant association was observed for sex and the follow-up durations stratified between tea consumption and type 2 diabetes.This meta-analysis indicates that tea consumption a parts per thousand yen4 cups per day may lower the risk of type 2 diabetes.