Hepatocellular pseudotumor in the cirrhotic liver: Report of three cases

Hepatocellular pseudotumor in the cirrhotic liver: Report of three cases
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肝硬化肝细胞性假瘤三例报告

DOI:
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发表时间:
1984
期刊:
影响因子:
6.2
通讯作者:
Isao Yuuki
Isao Yuuki
中科院分区:
医学1区
文献类型:
--
作者:
N. Nagasue;H. Akamizu;H. Yukaya;Isao Yuuki

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本文详细报道了3例肝硬变中再生的增生性结节。患者均为男性,年龄从41岁到57岁不等。他们都是酗酒者,有6到10年的慢性肝病。所有患者的α-胎儿蛋白水平都略有升高,HBs和HBc抗体均为阳性。除了超声检查显示所有病例的病变外,放射学结果并不一致。所有病例术前诊断均为肝细胞癌或高度怀疑肝细胞癌。剖腹手术时,所有病变均嵌在肝实质内,从肝脏表面看不到。在术中超声检查的帮助下,进行了部分肝切除。2例可见假包膜。肝硬变中再生结节与肝细胞癌的明确鉴别诊断是极其困难的。作者提出了“肝硬变肝细胞假瘤”的名称来描述这种病变。
Three cases of regenerating hyperplastic nodule in the cirrhotic liver are reported in detail. The patients were all men, ranging in age from 41 to 57 years. They were all heavy drinkers and had chronic liver disease for 6 to 10 years. All patients had slightly elevated α‐fetoprotein levels and were positive for HBs and HBc antibodies. Radiologic findings were not uniform except for ultrasonography, which demonstrated the lesion in all cases. Preoperative diagnosis was hepatocellular carcinoma (HCC) or highly suspicious of HCC in all of them. At laparotomy, all lesions were embedded in the liver parenchyma and invisible from the hepatic surface. With the aid of intraoperative sonography, partial hepatic resections were performed. Pseudocapsule was seen in two cases. Definitive differential diagnosis of regenerating nodules from HCC in the cirrhotic liver was extremely difficult. The authors propose the name “hepatocellular pseudotumor in the cirrhotic liver” to describe such lesions.