Pain sensitivity can be assessed by self-rating: Development and validation of the Pain Sensitivity Questionnaire
Pain sensitivity can be assessed by self-rating: Development and validation of the Pain Sensitivity Questionnaire
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DOI：
10.1016/j.pain.2009.06.020
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发表时间：
2009-11-01
期刊：
影响因子：
7.4
通讯作者：
Knecht, Stefan
中科院分区：
文献类型：
--
作者：
Ruscheweyh, Ruth;Marziniak, Martin;Knecht, Stefan
由于新出现的临床应用(包括术后疼痛和治疗反应的预测)和科学意义(例如，有人提出高于平均水平的疼痛敏感性是慢性疼痛障碍发生的危险因素)，疼痛敏感性的实验测定受到越来越多的关注。然而，由于实验疼痛敏感性评估对时间、设备和人力资源的要求，以及受试者的痛苦，阻碍了其在广泛范围内的应用。目前还缺乏实验性疼痛测试的替代方案。在这里，我们开发了一种用于评估疼痛敏感性的自我评级工具，即疼痛敏感性问卷(PSQ)，它基于日常生活情景的疼痛强度评级，需要5-10分钟才能完成。PSQ在354名受试者中被证实具有足够的可靠性。在一项包括47名健康受试者的验证性研究中，综合实验性疼痛测试的结果，包括不同的方式(热、冷、压力和针刺)和不同的测量(痛阈值、疼痛强度评级)，与PSQ的结果进行了比较。PSQ评分与实验疼痛强度分级显著相关(r=0.56p<；0.001)，但与痛阈值无关(r=0.03)。PSQ对实验性疼痛强度等级的预测比疼痛相关心理因素(疼痛灾变、抑郁、焦虑)更好。这表明PSQ可能是健康受试者实验疼痛强度分级程序的一种简单替代方法，并使PSQ成为临床和实验疼痛研究的一种非常有前途的工具。(C)2009年国际疼痛研究协会。爱思唯尔出版，版权所有。
Experimental determination of pain sensitivity has received increasing attention because of emerging clinical applications (including prediction of postoperative pain and treatment response) and scientific implications (e.g. it has been proposed that above-average pain sensitivity is a risk factor for the development of chronic pain disorders). However, the use of experimental pain sensitivity assessment on a broad scale is hampered by its requirements on time, equipment and human resources and the fact that it is painful for the tested subject. Alternatives to experimental pain testing are currently lacking. Here we developed a self-rating instrument for the assessment of pain sensitivity, the Pain Sensitivity Questionnaire (PSQ) that is based on pain intensity ratings of daily life Situations and takes 5-10 min to complete. Adequate reliability of the PSQ was confirmed in 354 subjects. In a validation study comprising 47 healthy subjects, the results of comprehensive experimental pain testing, including different modalities (heat, cold, pressure, and pinprick) and different measures (pain thresholds, pain intensity ratings), were compared to the results of the PSQ. PSQ scores were significantly correlated to experimental pain intensity ratings (r = 0.56, p < 0.001) but not to pain thresholds (r = 0.03). Prediction of experimental pain intensity ratings by the PSQ was better than by pain-associated psychological factors (pain catastrophizing, depression, anxiety). This shows that the PSQ may be a simple alternative to experimental pain intensity rating procedures in healthy subjects and makes the PSQ a highly promising tool for clinical and experimental pain research. (C) 2009 International Association for the Study of Pain. Published by Elsevier B.V. All rights reserved.