Clinical and epidemiological features of acute gastroenteritis caused by human rotavirus subgroups.
Clinical and epidemiological features of acute gastroenteritis caused by human rotavirus subgroups.
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人轮状病毒亚群引起的急性胃肠炎的临床和流行病学特征。
DOI：
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发表时间：
1992
期刊：
影响因子：
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通讯作者：
S. Broor
中科院分区：
文献类型：
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作者：
A. Chakravarti;S. Kumar;S. Mittal;S. Broor
在德里一年内住院的 288 名肠胃炎儿童中，有 44 名（15.28%）检测出轮状病毒。在这 44 名儿童中，分别有 13 名（29.55%）和 25 名（56.82%）儿童检出 I 亚型和 II 亚型轮状病毒。 5 名（11.36%）儿童的样本未与 I 亚组或 II 亚组单克隆抗体发生反应，表明存在第三亚组。在 1 例（2.27%）病例中检测到亚组 I 和 II。感染I亚型和II亚型轮状病毒的儿童的中位年龄分别为7个月和12个月。轮状病毒在男孩中比女孩中更常见。轮状病毒感染的高峰出现在初冬。每月最高和最低气温的差异与轮状病毒感染的发生率显着相关（p小于0.05）。 II 亚组是整个研究期间的主要群体，其严重腹泻的发生率明显高于 I 亚组。
Rotavirus was detected in 44 (15.28%) of 288 hospitalised children suffering from gastroenteritis in Delhi over a period of one year. Of these 44 children, subgroup I and II rotaviruses were detected in 13 (29.55%) and 25 (56.82%) children respectively. Samples from 5 (11.36%) children did not react with either subgroup I or II monoclonal antibodies, indicating the presence of a third subgroup. Both subgroups I and II were detected in one (2.27%) case. The median ages of the children infected by subgroup I and II rotavirus were 7 and 12 months respectively. Rotavirus was more prevalent in boys than in girls. The peak of rotavirus infection was seen in the early winter months. The difference of maximum and minimum monthly temperatures correlated significantly (p less than 0.05) with the incidence of rotavirus infection. Subgroup II was the predominant group throughout the period of study and caused a significantly higher incidence of severe diarrhoea than did subgroup I.