Alveolar ridge preservation using resorbable bioactive ceramic composite: a histological study.

Alveolar ridge preservation using resorbable bioactive ceramic composite: a histological study.
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使用可吸收生物活性陶瓷复合材料保存牙槽嵴:组织学研究。

DOI:
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发表时间:
2013
期刊:
Journal of the International Academy of Periodontology
影响因子:
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通讯作者:
A. el
A. el
中科院分区:
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文献类型:
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作者:
M. Al;J. Burt;Ahmed Barakat;Ahmad Kutkut;A. el

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目的 本研究的目的是在拔牙窝中使用生物活性和可吸收的二氧化硅-磷酸钙纳米复合材料(SCPC)多孔颗粒,对新生成的活骨进行组织学评价。 材料和方法 六名患者的上颌中切牙不可拔除,需要拔除后植入种植体,参与了这项研究。拔牙窝移植SCPC颗粒。6个月后,从愈合的牙槽窝中心取出骨芯样本进行组织学分析,并放置牙种植体。拔牙后即刻和植骨后6个月,在种植体植入时,对牙槽骨宽度进行临床评估。拔牙后立即和拔牙后6个月通过X线片评估牙槽骨高度。 结果 对使用SCPC移植6个月的牙槽骨进行组织形态学分析,发现46.8% +/- 14%的新活骨和2.5% +/- 1.5%的移植材料残留。在这些牙槽中,6个月愈合期内平均骨高度吸收为1.6 mm +/- 1.5 mm。在骨嵴处发现平均骨宽度吸收为2 mm +/- 0.7 mm。 结论 这项研究的结果表明,SCPC移植材料减少了拔牙后牙槽嵴尺寸的变化量,并促进了新的活骨的再生。
PURPOSE The purpose of this study was to histologically evaluate newly generated vital bone using porous granules of bioactive and resorbable silica-calcium phosphate nanocomposite (SCPC) in extraction sockets. MATERIAL AND METHODS Six patients with a non-restorable maxillary central incisor requiring extraction followed by implant placement participated in the study. Extraction sockets were grafted with granules of SCPC. After 6 months, a bone core sample was retrieved from the center of the healed socket for histologic analysis, and dental implants were placed. Alveolar bone width was clinically assessed immediately after tooth extraction and 6 months after bone grafting, at the time of implant placement. Alveolar bone height was radiographically assessed immediately after tooth extraction and 6 months after extraction. RESULTS Histomorphometric analyses of sockets grafted with SCPC for 6 months revealed 46.8% +/- 14% new vital bone and 2.5% +/- 1.5% graft material remnants. In these sockets, the mean bone height resorption over the 6-month period of healing was 1.6 mm +/- 1.5 mm. The mean bone width resorption of 2 mm +/- 0.7 mm was found at the bone crest. CONCLUSION The results of this study suggest that SCPC graft material reduces the amount of change in alveolar ridge dimensions after tooth extraction and facilitates the regeneration of new vital bone.